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Summary Expression Gene Literature (19) GO Terms (24) Nucleotides (313) Proteins (40) Interactants (236) Wiki
XB-GENEPAGE-957582
Gene Symbol:
smc3

Gene Name:
structural maintenance of chromosomes 3

Synonyms:
xsmc3 ( Add synonyms , Nomenclature history )

Gene Function:
Structural maintenance of chromosome protein 3 (sister chromatid cohesion complex Cohesin, subunit SMC3)

Protein Function :


InterPro :
LDL receptor-like sf , LDLR class-A CS , ConA-like dom sf , LDrepeatLR classA rpt [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
Cornelia de Lange syndrome

OMIM:
CORNELIA DE LANGE SYNDROME 3 WITH OR WITHOUT MIDLINE BRAIN DEFECTS; CDLS3

External Links:
 
Xenbase Gene ID XB-GENE-957583 XB-GENE-957588 XB-GENE-17331243
Gene Symbol smc3 smc3.L smc3.S
Chromosome Chr7 chr7L chr7S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100145671
399092
432330
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine smc3 smc3.L smc3.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SMC3 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Smc3 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Smc3 Ensembl
zebrafish
ZFIN, AGR smc3 ZFIN Ensembl
chicken
GEISHA SMC3 Ensembl
fruit fly
FLYBASE SMC3 Ensembl
worm
Publications
First Identification of Xenopus SMC protein complexes required for sister chromatid cohesion., Genes Dev 1998  
Most Recent Conservation and divergence of protein pathways in the vertebrate heart., PLoS Biol 2019                                                      
All View All Papers 1 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 18 terms 11 terms 7 terms
PANTHER smc3
KEGG Pathways K10844 K06669
KOG [D] Structural maintenance of chromosome protein 3 (sister chromatid cohesion complex Cohesin, subunit SMC3)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks smc3
Antibodies Smc3 Ab1 Smc3 Ab1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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