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Summary Expression Gene Literature (2) GO Terms (15) Nucleotides (156) Proteins (38) Interactants (129) Wiki
XB-GENEPAGE-957784
Gene Symbol:
keap1

Gene Name:
kelch like ECH associated protein 1

Synonyms:
INrf2 , klhl19 ( Add synonyms , Nomenclature history )

Gene Function:
Proteins containing BTB/POZ and Kelch domains, involved in regulatory/signal transduction processes

Protein Function :


InterPro :
Ig-like fold , Ig-like dom sf , FAM187A/B , Ig-like dom [+]

Interactants:
Loading ...

Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-957785 XB-GENE-957791 XB-GENE-17341150
Gene Symbol keap1 keap1.L keap1.S
Chromosome Chr3 chr3L chr3S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 493386
496326
108713336
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein NCBI Protein  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine keap1 keap1.L keap1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards KEAP1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Keap1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Keap1 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR keap1b keap1a ZFIN Ensembl
chicken
GEISHA KEAP1 Ensembl
fruit fly
FLYBASE Keap1 Ensembl
worm
Publications
First Insight into the intermolecular recognition mechanism between Keap1 and IKKβ combining homology modelling, protein-protein docking, molecular dynamics simulations and virtual alanine mutation., PLoS One 2013                  
Most Recent Dimerization quality control ensures neuronal development and survival., Science 2018  
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 15 terms 5 terms 5 terms
PANTHER keap1
KEGG Pathways K12668 [+] K10456 K10456
KOG [TR] Proteins containing BTB/POZ and Kelch domains, involved in regulatory/signal transduction processes
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks keap1
ORFs keap1 ORF1 keap1.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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