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Summary Expression Gene Literature (7) GO Terms (9) Nucleotides (110) Proteins (33) Interactants (398) Wiki
XB-GENEPAGE-960379
Gene Symbol:
ercc5

Gene Name:
excision repair cross-complementation group 5

Synonyms:
xpg , ercm2 , cofs3 , xpgc , uvdr ( Add synonyms , Nomenclature history )

Gene Function:
5'-3' exonuclease

Protein Function :
Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. Makes the 3'incision in DNA nucleotide excision repair (NER). Acts as a cofactor for a DNA glycosylase that removes ...[+]



Interactants:
Loading ...

Diseases: 


Disease Ontology:
xeroderma pigmentosum group G

OMIM:
CEREBROOCULOFACIOSKELETAL SYNDROME 1; COFS1 [+]

External Links:
 
Xenbase Gene ID XB-GENE-960380 XB-GENE-960384 XB-GENE-17342932
Gene Symbol ercc5 ercc5.L ercc5.S
Chromosome Chr02 chr2L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 100124735
397963
mRNA RefSeq RefSeq
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine ercc5 ercc5.L ercc5.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards ERCC5 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Ercc5 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Ercc5 Ensembl
zebrafish
ZFIN, AGR ercc5 ZFIN Ensembl
chicken
GEISHA ERCC5 Ensembl
fruit fly
worm
Publications
First Complementation of the DNA repair defect in xeroderma pigmentosum group G cells by a human cDNA related to yeast RAD2., Nature 1993  
Most Recent In vitro chromatin templates to study nucleotide excision repair., DNA Repair (Amst) 2015  
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 8 terms 5 terms 0 term
PANTHER ercc5
KEGG Pathways K10846 K10846
KOG [L] 5'-3' exonuclease (alt_id KOG:2520)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks ercc5
ORFs ercc5 ORF1 ercc5.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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