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Summary Expression Gene Literature (9) GO Terms (12) Nucleotides (161) Proteins (35) Interactants (59) Wiki
XB-GENEPAGE-961371
Gene Symbol:
mcm8

Gene Name:
minichromosome maintenance 8 homologous recombination repair factor

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
DNA replication licensing factor, MCM6 component

Protein Function :
Component of the MCM8-MCM9 complex, a complex involved in homologous recombination repair following DNA interstrand cross-links and plays a key role during gametogenesis. The MCM8-MCM9 complex probably...[+]



Interactants:
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Diseases: 


OMIM:
PREMATURE OVARIAN FAILURE 10; POF10

External Links:
 
Xenbase Gene ID XB-GENE-961372 XB-GENE-961378 XB-GENE-17342426
Gene Symbol mcm8 mcm8.L mcm8.S
Chromosome Chr05 chr5L
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 779797
734487
mRNA RefSeq RefSeq
Protein RefSeq Swiss-Prot RefSeq Swiss-Prot
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine mcm8 mcm8.L mcm8.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards MCM8 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Mcm8 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Mcm8 Ensembl
zebrafish
ZFIN, AGR mcm8 ZFIN Ensembl
chicken
GEISHA MCM8 Ensembl
fruit fly
worm
Publications
First MCM8 is an MCM2-7-related protein that functions as a DNA helicase during replication elongation and not initiation., Cell 2005  
Most Recent MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex., Nat Commun 2015                
All View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 12 terms 9 terms 0 term
PANTHER mcm8
KEGG Pathways K10737 K10737
KOG [L] DNA replication licensing factor, MCM6 component
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks mcm8
ORFs mcm8 ORF1
Clones Horizon Source BioScience Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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