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XB-GENEPAGE-
961444
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Gene Symbol: kif2c
Gene Name: kinesin family member 2C Synonyms: mcak , kcm1 , XKCM1 Add Xenopus synonyms , Nomenclature history Gene Function: Kinesin-like protein Protein Function  :
Promotes ATP-dependent removal of tubulin dimers from microtubules. Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis (PubMed:8548824). Ma...[+]
Interactants: Loading ... 
OMIM Disease Associations: |
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| Xenbase Gene ID | XB-GENE-961445 | XB-GENE-17344777 | XB-GENE-961451 | ||||||||||
| Gene Symbol | kif2c | kif2c.L | kif2c.S | ||||||||||
| Chromosome | Chr04 | chr4L | chr4S | ||||||||||
| Molecules | tropicalis | laevis.L | laevis.S | ||||||||||
| Gene |
Genomic sequence
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Genomic sequence
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Genomic sequence
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| CDS |
Gene model
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Entrez Gene
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Entrez Gene
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| mRNA |
Refseq
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Refseq
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| Protein
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Refseq
TrEMBL
TrEMBL
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TrEMBL |
Refseq
Swiss-Prot
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| Genomic | tropicalis | laevis.L | laevis.S | ||||||||||
| Genome Browser |
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| Genomic Synteny | Genomicus | ||||||||||||
| Expression | tropicalis | laevis.L | laevis.S | ||||||||||
| Ensembl | Ensembl | ||||||||||||
| UniGene | Str.45172 [+] | Xl.43865 | |||||||||||
| RNA-Seq profile | Stage profile: |
Stage profile:
Tissue heatmap:
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| Experimental regulation |
Regulation heatmap:
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| Images | 1 expression image(s) for tropicalis and laevis | ||||||||||||
| Data Mining | tropicalis | laevis.L | laevis.S | ||||||||||
| XenMine | kif2c | kif2c.L | kif2c.S | ||||||||||
| Phenotype | tropicalis | laevis.L | laevis.S | ||||||||||
| Smith Morpholino Screen | |||||||||||||
| Orthology |
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| Publications | |||||||||||||
| First: | XKCM1: a Xenopus kinesin-related protein that regulates microtubule dynamics during mitotic spindle assembly. [Cell 1996] | ||||||||||||
| Most recent: | Aurora A activation in mitosis promoted by BuGZ. [J Cell Biol 2018] | ||||||||||||
| View All Papers 1 paper(s) referencing morpholinos | |||||||||||||
| Functional Ontologies | tropicalis | laevis.L | laevis.S | ||||||||||
| GO | 7 terms | 5 terms | 12 terms | ||||||||||
| PANTHER | kif2c | ||||||||||||
| KEGG Pathways | K10393 | K10393 | K10393 | ||||||||||
| KOG |
[Z] Kinesin-like protein (alt_id KOG:0246)
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| Reagents | tropicalis | laevis.L | laevis.S | ||||||||||
| CRISPR / TALEN | CRISPR tools | CRISPR tools | CRISPR tools | ||||||||||
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| GE Dharmacon | GE Dharmacon | GE Dharmacon | |||||||||||
| Source BioScience | Source BioScience | ||||||||||||
| Antibody | Kif2c Ab1 , Kif2c Ab2 , Kif2c Ab3 | Kif2c Ab1 , Kif2c Ab2 , Kif2c Ab3 | |||||||||||
| ORF | kif2c ORF1 | ||||||||||||
| Affymetrix 1.0 | Str.4037.1.S1_at [+] | Xl.3533.1.S1_a_at [+] | |||||||||||
| Affymetrix 2.0 | Xl2.43865.1.S1_at | ||||||||||||
Symbol legend[+]
