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Summary Expression Gene Literature (4) GO Terms (5) Nucleotides (75) Proteins (25) Interactants (17) Wiki
Gene Symbol:

Gene Name:
solute carrier family 46 (folate transporter), member 1

( Add synonyms , Nomenclature history )

Gene Function:
Predicted transporter ADD1 (major facilitator superfamily)

Protein Function :
Has been shown to act both as an intestinal proton-coupled high-affinity folate transporter and as an intestinal heme transporter which mediates heme uptake from the gut lumen into duodenal epithelial ...[+]

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Disease Ontology:
hereditary folate malabsorption


External Links:
Xenbase Gene ID XB-GENE-961470 XB-GENE-961471 XB-GENE-17344183
Gene Symbol slc46a1 slc46a1.L slc46a1.S
Chromosome Chr2 chr2L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 100145771
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More..
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine slc46a1 slc46a1.L slc46a1.S
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
HGNC AGR, OMIM:Gene, GeneCards SLC46A1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
MGI, AGR Slc46a1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
RGD, AGR Slc46a1 Ensembl
ZFIN, AGR slc46a1 ZFIN Ensembl
GEISHA SLC46A1 Ensembl
fruit fly
First Rodent intestinal folate transporters (SLC46A1): secondary structure, functional properties, and response to dietary folate restriction., Am J Physiol Cell Physiol 2007  
Most Recent The monomeric state of the proton-coupled folate transporter represents the functional unit in the plasma membrane., FEBS J 2013  
All View All Papers 1 paper(s) referencing OMIMs
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 4 terms 5 terms 0 term
PANTHER slc46a1
KEGG Pathways K14613 K14613
KOG [R] Predicted transporter ADD1 (major facilitator superfamily)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks slc46a1
ORFs slc46a1.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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