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Summary Expression Gene Literature (10) GO Terms (14) Nucleotides (95) Proteins (34) Interactants (414) Wiki
XB-GENEPAGE-964442
Gene Symbol:
lig4

Gene Name:
ligase IV, DNA, ATP-dependent

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
ATP-dependent DNA ligase IV

Protein Function :


InterPro :
Kinase-like dom sf , Transforming GF b rcpt 2 ecto , Ser-Thr/Tyr kinase cat dom , TGFB receptor [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
Omenn syndrome [+]

OMIM:
LIG4 SYNDROME [+]

External Links:
 
Xenbase Gene ID XB-GENE-964443 XB-GENE-964449 XB-GENE-17343804
Gene Symbol lig4 lig4.L lig4.S
Chromosome Chr2 chr2L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 549735
394389
mRNA RefSeq NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine lig4 lig4.L lig4.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards LIG4 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Lig4 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Lig4 Ensembl
zebrafish
ZFIN, AGR lig4 ZFIN Ensembl
chicken
GEISHA LIG4 Ensembl
fruit fly
FLYBASE DNAlig4 Ensembl
worm
Publications
First DNA ligase III promotes alternative nonhomologous end-joining during chromosomal translocation formation., PLoS Genet 2011              
Most Recent XLF acts as a flexible connector during non-homologous end joining., Elife 2020                    
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 13 terms 8 terms 0 term
PANTHER lig4
KEGG Pathways K10777 K10777
KOG [L] ATP-dependent DNA ligase IV
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks lig4
ORFs lig4.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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