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Summary Expression Gene Literature (1) GO Terms (5) Nucleotides (112) Proteins (44) Interactants (59) Wiki
XB-GENEPAGE-964635
Gene Symbol:
klhl25

Gene Name:
kelch like family member 25

Synonyms:
Xencr-2 , enc2 ( Add synonyms , Nomenclature history )

Gene Function:
Proteins containing BTB/POZ and Kelch domains, involved in regulatory/signal transduction processes

Protein Function :
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for translational homeostasis. The BCR(KLHL25) ubiquitin ligase complex acts by mediating ubiquitination of hypo...[+]


InterPro :
BTB/POZ dom , KLHL25 , BTB-kelch protein , Kelch 1 [+]

Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-964636 XB-GENE-964642 XB-GENE-17344683
Gene Symbol klhl25 klhl25.L klhl25.S
Chromosome Chr3 chr3L chr3S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 779996
398575
108712836
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. NCBI Protein NCBI Protein  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine klhl25 klhl25.L klhl25.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, KLHL25 Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Klhl25 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Klhl25 Ensembl
zebrafish
klhl25 Ensembl
chicken
GEISHA KLHL25 Ensembl
fruit fly
worm
Publications
First A family of Xenopus BTB-Kelch repeat proteins related to ENC-1: new markers for early events in floorplate and placode development., Gene Expr Patterns 2003        
Most Recent
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 5 terms 4 terms 3 terms
PANTHER klhl25
KEGG Pathways K10462 K10462 K10462
KOG [TR] Proteins containing BTB/POZ and Kelch domains, involved in regulatory/signal transduction processes
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks klhl25
ORFs klhl25 ORF1 klhl25.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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