Gene Symbol : klhl25 Gene Name : kelch like family member 25 Synonyms: Xencr-2 , enc2 ( Add synonyms , Nomenclature history ) Gene Function: Proteins containing BTB/POZ and Kelch domains, involved in regulatory/signal transduction processes Protein Function : Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for translational homeostasis. The BCR(KLHL25) ubiquitin ligase complex acts by mediating ubiquitination of hypo...[+] Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for translational homeostasis. The BCR(KLHL25) ubiquitin ligase complex acts by mediating ubiquitination of hypophosphorylated eif4ebp1 (4E-BP1). [-] Interactants: Loading ... Diseases:  External Links: ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD

Expression	Development Stages                                               Embryonic Tissuesd                                                                Adult Tissues
More Information	Xenbase Expression Details In situ images Single cell data at SPRING

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