Gene Symbol: crhr1.2 Gene Name: corticotropin releasing hormone receptor 1, gene 2 Synonyms: crf-r1 Add Xenopus synonyms Gene Function: adenylate cyclase-coupled calcitonin receptor Interactants: crh(4) , crhr2(2) , vip(1) , View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		NCBI Nucleotide >XM_002937993|PREDICTED: Xenopus (Silurana) tropicalis corticotropin-releasing factor receptor 1-like (LOC100498637), partial mRNA GTTATCACTGCTGGGATCAGTTTTGCCCTCACCTCTCTCCAGGACCAATGTGAAACCCTGCAGCACAATTCTAATGTTACAGGTCTCGCCTGTAACGCTTCCATTGATATGATCGGCACTTGTTGGCCTCGCACTGCAGCTGGACAGATGGTGGCCAGACCCTGCCCTGAGTACTTCCAGGGGGTGCAATACAATACAACAGGGAATGTCTACAGAGAGTGTCACCTGAACGGCAGCTGGGCTGGGAGAGGAGACTACACTCAGTGCCAGGAGATTCTGAAGCAGGAGAAGAAAACCAAAGTTCATTATCACATAGCCATTGTGATCAACTTCCTTGGTCACTCCATCTCCCTTTGTGCCCTCCTGGTGGCTTTTATCCTCTTCTTAAGGTTGAGGAGCATCCGGTGCCTGCGTAACATCATCCACTGGAACCTGATCACGGCTTTCATTCTGCGCAATGTAACCTGGTTTGTGATGCAGCTCACTCTCAGCCACGAAGCACACGACAGCAACGTGGTTTGGTGCCGCCTGGTCACCATCGCTCACAATTATTTTTACGTTACCAACTTCTTCTGGATGTTTGGGGAGGGCTGTTACCTACACACGGCTATTGTGCTAACCTACTCGACCGACAAACTGCGCAAATGGATGTTCATCTGTATCGGCTGGTGTATTCCCTTTCCCATCATTGTGGCTTGGGCCATTGGCAAACTTTACTATGACAATGAAAAGTGCTGGTTTGGTAAGAAAGCAGGAGTCTACACAGATTTTATCTACCAGGGTCCGGTTATCCTTGTACTGCTGATCAACTTTATATTTTTATTCAACATAGTGCGGATTCTGATGACAAAGCTCCGAGCTTCCACCACTTCAGAGACCATACAGTACAGGAAAGCAGTTAAAGCCACCCTGGTGCTCCTGCCCTTGCTTGGGATCACCTACATGCTTTTCTTTGTGACGCCTGGGGAGGATGAAATTTCACGTGTAGTCTTTATCTACTTCAACTCTTTCCTGCAGTCCTTTCAGGGTTTCTTTGTATCGGTGTTCTACTGCTTCCTTAATAGTGAGGTGCGTTCAGCAGTCCGGAAGCGATGGCACCGCTGGCAGGACAAGCATTCGATCCGCGCTCGTGTGGCCCGCGCTATGTCCATTCCCACATCGCCCACACGGATTAGTTTCCACAGCATCAAGCAATCTTCTGCCATTTGAACTTAGTCTCCATGAGAGTTTCCCTTAAGCCCCTGCTCTCCTGGAACTCCTCAAACCCTCACAAGACAAGTCATCTTCTGAATGGCTGAAGAGGGTTTGTCCTCCTGCGTGGTTTCCAGCTTTGCCCATGTACCAGGGGCCAATAACTTATCTTCAACTAGACGGACCAAGACAATCAACACAAGATAACAGCCGAGTGCAGGTACCACAAGGGAGGTTCCACAAGCAAGAGCAAAGTACTGGCACTGCCAGGCCCCAGGGCAGACACAGGACTCTGCACACAGCACAATTCATTCACTGATTTATCACCAGCCAGGTGCAAATGAACTCTGAGAGCCACAGTTTATGATTTTTCCAAAGGGAATGGATGATCACAATATGGATCCTCTTTTCAGTGCCTGGAGAAGCAGGCCACACCAGCACCAGACCAAGCAACTGCATCTGAACGAATGGGAAGCCCTACACAACAAGTATAATCATTCTCAACAAACAAATACAAGCACAAAGTATTACATATATATATATACATATTTGTGTGCTGTGCACTGGGGTCTGCATCAGTGCATTCTGGAACATCATTCAATGAAGATGTTTATCCATGAATTCTATGTCATGTGGAAATATGTCATGTGGACCAGAAAGGGCAGTAGATCAAGACTTCCAGGTGTCTCTGCCGAGACGATTCCTGTAGATGAACTTTAACAGGCTGAGGTCTATATTTTCTGTAACTCTTCAGTCTGTAAGCATAATCTTGTTTATATGTTATTCTGTGGAATTTAGGTATAAATCAGAACGCCTA	Refseq >NM_001085580|Xenopus laevis corticotropin releasing hormone receptor 1, gene 2 (crhr1.2), mRNA ATGCTGTTGGCCAAAACTCCATGTCTACTACTGGTGCAGGTGATCGCTGCTGGAATCAGTTTTGCCCTCACCTCTCTCCAGGACCAATGTGAAACCCTGCAGCACAATTCTAACTTCACAGGTCTTGCCTGCAACGCTTCCATTGATATGATCGGCACTTGCTGGCCCAGTACTGCAGCTGGACAGATGGTGGCCAGACCCTGCCCCGAGTACTTCCATGGGGTGCAATACAACACAACAGGGAATGTGTACAGAGAATGTCACCTGAACGGCAGCTGGGCTGGGAGAGGAGACTACGCTCAATGCCAGGAGATTCTAAAGCAAGAGAAGAAAACCAAAGTTCATTATCACATAGCCATCGTGATTAACTTCCTGGGTCACTCCATTTCCCTTTGTGCTCTCCTGGTGGCTTTTATCCTGTTCTTGAGGTTGAGGAGCATCCGGTGCCTACGTAATATCATCCACTGGAACCTGATCACGGCTTTTATTCTGCGTAATGTAACCTGGTTTGTGATGCAGCTCACTCTCAGCCATGAAGCCCACGACAGCAATGTGGTTTGGTGCCGCCTGGTCACCATCGCTCACAATTATTTTTATGTTACCAACTTCTTCTGGATGTTTGGGGAGGGCTGTTACCTGCACACGGCCATTGTTCTAACCTACTCAACTGACAAACTGCGCAAATGGATGTTCATCTGTATTGGCTGGTGTATCCCCTTTCCCATCATTGTGGCTTGGGCCATTGGCAAACTTTACTACGACAATGAAAAGTGCTGGTTTGGGAAGAAAGCGGGAGTCTACACAGATTTTATCTACCAAGGACCTGTCATCCTTGTGCTGCTGATCAACTTCATATTTTTATTCAACATTGTACGGATTCTGATGACAAAGCTCAGAGCTTCCACCACTTCAGAGACCATACAGTACAGGAAAGCTGTTAAAGCCACCCTGGTGCTCCTGCCTTTGCTTGGGATCACCTACATGCTTTTCTTTGTGACGCCCGGGGAGGATGAAATCTCACGTATCGTCTTTATCTATTTCAACTCTTTCCTGCAGTCCTTTCAGGGTTTCTTTGTTTCAGTTTTCTACTGCTTCCTTAATAGTGAGGTGCGCTCAGCAGTCCGGAAGCGATGGCACCGATGGCAGGACAAGCATTCAATCCGTGCTCGCGTGGCCCGTGCCATGTCCATTCCCACATCACCCACTCGGATTAGTTTCCACAGCATCAAGCAATCTTCTGCCATTTGA
Protein		NCBI Protein >XP_002938039|PREDICTED: corticotropin-releasing factor receptor 1-like, partial [Xenopus (Silurana) tropicalis] VITAGISFALTSLQDQCETLQHNSNVTGLACNASIDMIGTCWPRTAAGQMVARPCPEYFQGVQYNTTGNVYRECHLNGSWAGRGDYTQCQEILKQEKKTKVHYHIAIVINFLGHSISLCALLVAFILFLRLRSIRCLRNIIHWNLITAFILRNVTWFVMQLTLSHEAHDSNVVWCRLVTIAHNYFYVTNFFWMFGEGCYLHTAIVLTYSTDKLRKWMFICIGWCIPFPIIVAWAIGKLYYDNEKCWFGKKAGVYTDFIYQGPVILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVTPGEDEISRVVFIYFNSFLQSFQGFFVSVFYCFLNSEVRSAVRKRWHRWQDKHSIRARVARAMSIPTSPTRISFHSIKQSSAI	Refseq >NP_001079049|corticotropin-releasing factor receptor 1 precursor [Xenopus laevis] MLLAKTPCLLLVQVIAAGISFALTSLQDQCETLQHNSNFTGLACNASIDMIGTCWPSTAAGQMVARPCPEYFHGVQYNTTGNVYRECHLNGSWAGRGDYAQCQEILKQEKKTKVHYHIAIVINFLGHSISLCALLVAFILFLRLRSIRCLRNIIHWNLITAFILRNVTWFVMQLTLSHEAHDSNVVWCRLVTIAHNYFYVTNFFWMFGEGCYLHTAIVLTYSTDKLRKWMFICIGWCIPFPIIVAWAIGKLYYDNEKCWFGKKAGVYTDFIYQGPVILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVTPGEDEISRIVFIYFNSFLQSFQGFFVSVFYCFLNSEVRSAVRKRWHRWQDKHSIRARVARAMSIPTSPTRISFHSIKQSSAI UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.38450	Xl.52 [+] Xl.18907
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	CRHR1
mouse		MGI	Crhr1	All(12) Targeted, knock Out(3) Targeted, other(3)
zebrafish		ZFIN	crhr1	7 Lines(s)

Publications
First:		Identification of two corticotropin-releasing factor receptors from Xenopus laevis with high ligand selectivity: unusual pharmacology of the type 1 receptor. [J Neurochem 1997]
Most recent:		Characterization of three corticotropin-releasing factor receptors in catfish: a novel third receptor is predominantly expressed in pituitary and urophysis. [Endocrinology 2001]
		View All Papers

Functional Ontologies
GO: Molecular:		G-protein coupled receptor activity
Biological:
Cellular Component:		membrane
EC:
KOG:		[T] Adenylate cyclase-coupled calcitonin receptor

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		StrJgi.3635.1.S1_s_at [+] Str.38450.2.A1_x_at	Xl.52.1.S1_at [+] Xl.18907.1.A1_at
Affymetrix 2.0			Xl2.52.1.S1_at [+] Xl2.18907.1.A1_at

Symbol legend[+]

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