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Summary Expression Gene Literature (1) GO Terms (39) Nucleotides (165) Proteins (48) Interactants (31) Wiki
XB-GENEPAGE-968564
Gene Symbol:
fbxl5

Gene Name:
F-box and leucine-rich repeat protein 5

Synonyms:
fbl5 ( Add synonyms , Nomenclature history )

Gene Function:
F-box protein containing LRR

Protein Function :
Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of ireb2/irp2. Upon high iron a...[+]


InterPro :
Leu-rich rpt , Haemerythrin-like , F-box-like dom sf , Leu-rich rpt Cys-con subtyp [+]

Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-968565 XB-GENE-968570 XB-GENE-17335521
Gene Symbol fbxl5 fbxl5.L fbxl5.S
Chromosome Chr1 chr1L chr1S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 496483
432131
380440
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine fbxl5 fbxl5.L fbxl5.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards FBXL5 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Fbxl5 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Fbxl5 Ensembl
zebrafish
ZFIN, AGR fbxl5 ZFIN Ensembl
chicken
GEISHA FBXL5 Ensembl
fruit fly
worm
Publications
First Identification of novel F-box proteins in Xenopus laevis., Curr Biol 1999      
Most Recent
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 38 terms 6 terms 1 terms
PANTHER fbxl5
KEGG Pathways K10271 K10271 K10271
KOG [R] F-box protein containing LRR
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks fbxl5
ORFs fbxl5.L ORF1 fbxl5.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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