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Summary Expression Gene Literature (2) GO Terms (19) Nucleotides (141) Proteins (38) Interactants (225) Wiki
XB-GENEPAGE-970898
Gene Symbol:
xrcc6

Gene Name:
X-ray repair complementing defective repair in Chinese hamster cells 6

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
DNA-binding subunit of a DNA-dependent protein kinase (Ku70 autoantigen)

Protein Function :
Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched...[+]



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-970899 XB-GENE-970904 XB-GENE-17331947
Gene Symbol xrcc6 xrcc6.L xrcc6.S
Chromosome Chr04 chr4L
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 448213
398357
mRNA RefSeq RefSeq
Protein RefSeq RefSeq
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine xrcc6 xrcc6.L xrcc6.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards XRCC6 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Xrcc6 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Xrcc6 Ensembl
zebrafish
ZFIN, AGR xrcc6 ZFIN Ensembl
chicken
GEISHA XRCC6 Ensembl
fruit fly
worm
Publications
First Gradual loss of DNA-PK activity from the cytoplasm is coincident with the nuclear translocation of its activator Ku during early development of Xenopus laevis., Folia Biol (Praha) 2009  
Most Recent Conservation and divergence of protein pathways in the vertebrate heart., PLoS Biol 2019                                                      
All View All Papers 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 19 terms 7 terms 0 term
PANTHER xrcc6
KEGG Pathways K10884 K10884
KOG [L] DNA-binding subunit of a DNA-dependent protein kinase (Ku70 autoantigen)
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks xrcc6
ORFs xrcc6 ORF1 xrcc6.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience

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