Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (0) GO Terms (10) Nucleotides (147) Proteins (28) Interactants (10) Wiki
XB-GENEPAGE-971666
Gene Symbol:
nae1

Gene Name:
NEDD8 activating enzyme E1 subunit 1

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
NEDD8-activating complex, APP-BP1/UBA5 component

Protein Function :
Regulatory subunit of the dimeric uba3-nae1 E1 enzyme. E1 activates nedd8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalyti...[+]



Interactants:
Loading ...

Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-971667 XB-GENE-17330459 XB-GENE-971671
Gene Symbol nae1 nae1.L nae1.S
Chromosome Chr04 chr4S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 100145030
414612
mRNA RefSeq RefSeq
Protein NCBI Protein RefSeq RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine nae1 nae1.L nae1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards NAE1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Nae1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Nae1 Ensembl
zebrafish
ZFIN, AGR nae1 ZFIN Ensembl
chicken
GEISHA NAE1 Ensembl
fruit fly
worm
Publications
First
Most Recent
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 10 terms 0 term 2 terms
PANTHER nae1
KEGG Pathways K04532 K04532
KOG [O] NEDD8-activating complex, APP-BP1/UBA5 component
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks nae1
ORFs nae1.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.15.0
Major funding for Xenbase is provided by grant P41 HD064556