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Summary Expression Gene Literature (2) GO Terms (5) Nucleotides (295) Proteins (55) Interactants (140) Wiki
XB-GENEPAGE-972412
Gene Symbol:
dnajb6

Gene Name:
DnaJ heat shock protein family (Hsp40) member B6

Synonyms:
DnaJ , hsj2 , dnajb6-a , dnajb6-b ( Add synonyms , Nomenclature history )

Gene Function:
Molecular chaperone (DnaJ superfamily)

Protein Function :
Plays an indispensable role in the organization of krt8/krt18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Has a stimulatory effect on the ATPase act...[+]



Interactants:
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Diseases: 


Disease Ontology:
autosomal dominant limb-girdle muscular dystrophy type 1E

OMIM:
MUSCULAR DYSTROPHY, LIMB-GIRDLE, AUTOSOMAL DOMINANT 1; LGMDD1

External Links:
 
Xenbase Gene ID XB-GENE-972413 XB-GENE-954099 XB-GENE-972418
Gene Symbol dnajb6 dnajb6.L dnajb6.S
Chromosome Chr6 chr6L chr6S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 394712
734291
495138
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine dnajb6 dnajb6.L dnajb6.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards DNAJB6 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Dnajb6 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Dnajb6 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR dnajb6a dnajb6b ZFIN Ensembl
chicken
GEISHA DNAJB6 Ensembl
fruit fly
worm
Publications
First A DNAJB chaperone subfamily with HDAC-dependent activities suppresses toxic protein aggregation., Mol Cell 2010                
Most Recent DnaJB6 is a RanGTP-regulated protein required for microtubule organization during mitosis., J Cell Sci 2019              
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 5 terms 2 terms 2 terms
PANTHER dnajb6
KEGG Pathways K09512 K09512 K09512
KOG [O] Molecular chaperone (DnaJ superfamily) (alt_id KOG:0714)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks dnajb6
ORFs dnajb6 ORF1 dnajb6.L ORF1 dnajb6.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info