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Summary Expression Gene Literature (4) GO Terms (28) Nucleotides (526) Proteins (47) Interactants (120) Wiki
XB-GENEPAGE-975055
Gene Symbol:
dusp1

Gene Name:
dual specificity phosphatase 1

Synonyms:
XCL100 ( Add synonyms , Nomenclature history )

Gene Function:
MAP kinase phosphatase

Protein Function :
Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-188' and 'Tyr-190', regulating its activity during the meiotic cell cycle.



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-975056 XB-GENE-975062 XB-GENE-17344125
Gene Symbol dusp1 dusp1.L dusp1.S
Chromosome Chr3 chr3L chr3S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 448043
380262
398254
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine dusp1 dusp1.L dusp1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards DUSP1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Dusp1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Dusp1 Ensembl
zebrafish
ZFIN, AGR dusp1 ZFIN Ensembl
chicken
GEISHA DUSP1 Ensembl
fruit fly
worm
Publications
First XCL100, an inducible nuclear MAP kinase phosphatase from Xenopus laevis: its role in MAP kinase inactivation in differentiated cells and its expression during early development., J Cell Sci 1995  
Most Recent Dusp1 modulates activin/smad2 mediated germ layer specification via FGF signal inhibition in Xenopus embryos., Anim Cells Syst (Seoul) 2020              
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 21 terms 14 terms 14 terms
PANTHER dusp1
KEGG Pathways K21278 [+] K04459 [+] K21278 [+]
KOG [V] Dual specificity phosphatase
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks dusp1
ORFs dusp1 ORF1 dusp1.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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