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Summary Expression Gene Literature (4) GO Terms (13) Nucleotides (134) Proteins (27) Interactants (92) Wiki
XB-GENEPAGE-976484
Gene Symbol:
itch

Gene Name:
itchy E3 ubiquitin protein ligase

Synonyms:
itchy ( Add synonyms , Nomenclature history )

Gene Function:
ubiquitin-protein ligase

Protein Function :


InterPro :
E3 ub ligase SMURF1 , HECT dom , Hect E3 ubiquitin ligase , WW dom [+]

Interactants:
Loading ...

Diseases: 


OMIM:
AUTOIMMUNE DISEASE, MULTISYSTEM, WITH FACIAL DYSMORPHISM; ADMFD

External Links:
 
Xenbase Gene ID XB-GENE-976485 XB-GENE-6486380 XB-GENE-17340217
Gene Symbol itch itch.L itch.S
Chromosome Chr10 Scaffold24211
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 6.0
CDS Gene model
Entrez Gene 780194
mRNA RefSeq
Protein NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine itch itch.L itch.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards ITCH OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Itch MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Itch Ensembl
zebrafish
ZFIN, AGR itcha itchb ZFIN Ensembl
chicken
GEISHA ITCH Ensembl
fruit fly
worm
Publications
First Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex., Genes Dev 2002    
Most Recent Understanding MAPK Signaling Pathways in Apoptosis., Int J Mol Sci 2020            
All View All Papers 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 13 terms 0 term 0 term
PANTHER itch
KEGG Pathways K05632
KOG [O] Ubiquitin protein ligase RSP5/NEDD4
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks itch
ORFs itch ORF1
Clones Horizon Source BioScience Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info