Gene Symbol: cav2 Gene Name: caveolin 2 Synonyms: caveolin-2, Cav-2 Add Xenopus synonyms Gene Function: Interactants: cacna1a(21) , cav1(13) , cacna1b(11) , cacna1c(11) , cacna1e(9) , cacnb3(5) , cav3.1(5) View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001015763|Xenopus (Silurana) tropicalis caveolin 2 (cav2), mRNA AGGAGAAGGAGGCACCGCACCCCGGGAGTGGGCTCTGAGCAGCAACCGGGCTCTGACTCCGGAGACATGGGCCTCGAAAAGGAGAAGGCAGATGCCCGCATTTTCATGGATGAAGATGAACTGAATCACTCCACTGTCCCGATGCTGACAGAAAAAACATTCGACAACAGCCCCGACCGTGACCCCCACAAGCTGAACTCCCACCTGAAGATAGGCTTTGAGGATGTGATCGGAGAGCCAGATACAACTCACAGCTTTGACAGGGTCTGGGTGTTCAGCACAGCTCTGTTTGAGATCAGCAAATACCTGATCTACAAGGTCCTGAGTGTTCTGCTTGCCGTGCCGCTGGCATTTGTAATGGGAATACTGTTCGCAGTGCTCAGCTGCCTACACATTTGGATTGTGATGCCTTTTGTGAAGACCTGTATGATGATGTTTCCTTCTGTACAGATAATATGGAAGGGTGTGACAGATAGCTTAATTGCTCCCTTATTTGCAAGCATGGGACGTTGTCTTTCTAGTGTTAATGTTCAGCTGGATCGGGATTAAGCCTATGTACCCCACTGTGATACTGACCGTCTCTGCCTTCTTGGTGCTGAAACACTCTGCTCCCTTGTGCACTATGATCAGATAATATGAAGCAACTCATAGAATACACTCTTAACACCAACTGTGTACATAGTGCATAAAACAGTAAGTTTTGTAGCTAATGTATAAGCTATGCACAGTTAACCACCTGATCAGTGGGAATGTACTAAAAAGAGCATATGTCCATTTAGCAATAAATGGATGTACAGAAATGTCACTATTTCTTATGGACTCCCAGTTATCTGACTTTTAGGCACAGGAATCGATAAATATGTATTAAGCTTTACATTTAGTATACTGAGCTCAGTTTTTTCAGTGCTATCTGGATTAAAATGAAGCCTAAAGAAAAAGGTAACTGCAAGGCAAGAGTTTCTCAGTTACAATATGTTACTGCTCATATCATTATGGATGTCAGAACTGCAGCTTTCCCATTGTTTGTCCCATTGTTGTCTAAAGGTTGTATTGGGAAAATGGGGGGGTTGCAGTGCCACAAAAGCTAGATACAAACCGGAAGTTCCAAGCTTGTTGTGTGGGGAAAAGGAGTTCCAAGCTTGTTGTGTTGGCCCCATAAGAGTGAAATGTTGATGTGAATGCTTATTAGCTGTCTTGAACACGAGCAGCGGTTCTGTAAACAAACACTTGTAACATAAGCCACGGGACCACATTTTGGATCACAAAAGAGCATTTGAACCCAAAAGGTCTGAAAACCACTGTCTAAACTAAATAAATAGTTCCCCGGAATCCTCAATGGAAACCCTCTGCTATGTTTTTGGACAGCCACATCTGATCATTATGCCACTGAAAACAAGTCTTGCTGTTGCCACTGGATTCTACCAATGACATGCTACCTGCCTGCTGACCTAAACTAACTGGCATTAAACTAAACCTTGATATCAAGTCTTTACAGAACTGCTGTAACATATGTTTGGAATAAGTTCAGCCGGGAAACTTTTAGACAATACCAACACTCAAAATGATAGCTTTTACAGATCACATATTTAATGTTTATTTACTAAGGGCACAGTGTACAAATCATGTTAATTATATAAGAGCAATGCACTGAAATAATCTGTAGAGATTAAATAAATATTTTGAAA	Refseq >NM_001088829|Xenopus laevis caveolin 2 (cav2), mRNA CAAGCAGTGGGCTGTAAGCAGCAACCGGGCTCCCGCTCCGGAGACATGGGCCTCGAGAAGGAGACGTTAGATGCCCGCATTTTTATGGACGAAGATGAACTGAATCACAGCACTGTCCCCATGCTCACTGAAAAGACATTCGACAACAGCCCCGACCGTGATCCCAAGAGGCTGAACTCCCACCTGAAGATAGAGTTTGAGGATGTGATCGGAGAGCCAGATACAACTCACAGCTTCGACAGGGTCTGGGTGTGCAGCACAGCTCTGTTTGAAATCAGCAAATACCTGATCTACAAGGTCCTCACTGTCCTACTTGCTGTGCCGCTGGCATTTGTAATGGGAATACTATTTGCAGTGCTCAGCTGTCTACACATTTGGATTATGATGCCTTTCGCGAAGACCTGTATGATGATTTTGCCTTCTGTACAGAAGATATGGAAGGGCGTGACAGATAGCTTTATTGCTCCCTTATTTGCAAGCATGGGACGGTGTATGTCTAGCATTAACATTCAGCTGGATCGGGATTAAGCCTCTGTACCCCTTTGTAATACTGAATGTCTCTGCCTTTTTGGTGCTGAAACACTCTGCTCCCTCTTGCACCATGATCAGATGAAATAAAGCTACTCATAGACTATGCACCTTATCTTAACAGCATATTTAAATATTGCATAAAGCTGAAACACTGGCTCAAGTCTAGTAACCAGTTAAAGTCTGAATTTGCATAATTTACCACCTGATCAGTGGACATGTATTCAAAACATATGTTCATGCAGAAATGTGGGACATTATACTATTAATTCTGATGTAGAGGTGTCATTTAGCATTTTTTATGGACTCCAGTATTTCTTGAACTGCCTTTAAGCACGGGAATGGGTAATATGTATTAAGCTTTACATTTAGTATACTGATTTCAGTCTTTTCAGTGCTATGTGGATTAAAATGAAGTCTAAAGAAAAAGGTGAATGCTAGGCAAGAGTTTCTCTGGTATCTATTACAGTATGTTACTGTTCCCTGTGAGTAACATGATACTTTAAGGATATATCATTATAATATCAAGCCTGCAGCATTCCATTTGTTTTTAAAGGATGCCTTGGGTGCCACAATTTCTGAAGGACCACAAGCTGGACATTCCTGGTATATCGGTAACAGATACATAGGCTTAGTCTAAACCTGAGGTTCCAAGCTTGTTGAGTGTGGGGCATAGCAGTGAATTTTGACCCCCAATAAGACTGAAATGATGGGATGAATGTTTATTACCTGTCCTGAATAATACCAGTGAGGCTGTTAACAAACATTTGTAGCGTAAGCCAGGGGAGCCTGACCACATTTTGGATTACAAAAGAGAATTTGAACCCAAAAGGTCTAAAGACAACTTTCTAAACCAAAGAGATGGTTTTGTGAGAATCCCTAATGGCAGCCCTCTTACTGGGTGTTCACATCCAATCTTTATGTCACCGAGAACAAGCCATGCTATTTCCAATGGATTTTACCATGACATGCTACCCTTCTGCTCATCTTAGCTAACTGGCATCAAACTAAACCTTAATATCAAGTCTATGCAGAACTGCTGTAACAGAGTTTTTTCAAAAAAGATTAGTTGGGAAACTTTCAGATAATTTCAACACTCAAAATGATAAAAATGACAGATCATGTATTTAATGTTTATTGACTAAGGGTTGCCGGAGCTGCCGATGCTACCTATTTCTTACGTTATTTACTGAGGGCACAATGTAAAACCCATGTTAAATATATAAGAGCAATGCACTGAAATAATTCTGTAGAGATTAAATAAATATATTGAAACATTTCTTAACAAACAGCGTATGCTTGTGTATCTATGGAGAGAGTATTTGTTTAAAGTGTAAAGTCTCATTTTACTATGCTATACCAGTAATTTCCCAGCTGTTGGGATGATACATCATAGGTTGACAATCATTATTCTGTACTACTAAATAAAATAGAAGGCTAAAAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001015763|caveolin 2 [Xenopus (Silurana) tropicalis] MGLEKEKADARIFMDEDELNHSTVPMLTEKTFDNSPDRDPHKLNSHLKIGFEDVIGEPDTTHSFDRVWVFSTALFEISKYLIYKVLSVLLAVPLAFVMGILFAVLSCLHIWIVMPFVKTCMMMFPSVQIIWKGVTDSLIAPLFASMGRCLSSVNVQLDRD	Refseq >NP_001082298|caveolin 2 [Xenopus laevis] MGLEKETLDARIFMDEDELNHSTVPMLTEKTFDNSPDRDPKRLNSHLKIEFEDVIGEPDTTHSFDRVWVCSTALFEISKYLIYKVLTVLLAVPLAFVMGILFAVLSCLHIWIMMPFAKTCMMILPSVQKIWKGVTDSFIAPLFASMGRCMSSINIQLDRD

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.8533 [+] Str.51950	Xl.32904
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		34 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	CAV2
mouse		MGI	Cav2	All(3) Targeted, knock Out(3)
zebrafish		ZFIN	cav2

Publications
First:		Molecular determinants of inactivation within the I-II linker of alpha1E (CaV2.3) calcium channels. [Biophys J 2001]
Most recent:		Two sets of amino acids of the domain I of Cav2.3 Ca(2+) channels contribute to their high sensitivity to extracellular protons. [Pflugers Arch 2011]
		View All Papers

Functional Ontologies
GO: Molecular:
Biological:
Cellular Component:		caveolar membrane
EC:
KOG:

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.8533.1.A1_s_at	Xl.5491.1.S1_at
Affymetrix 2.0			Xl2.32904.1.S2_at

Symbol legend[+]

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