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Summary Expression Gene Literature (1) GO Terms (10) Nucleotides (336) Proteins (46) Interactants (117) Wiki
XB-GENEPAGE-977708
Gene Symbol:
uba2

Gene Name:
ubiquitin like modifier activating enzyme 2

Synonyms:
sae2 ( Add synonyms , Nomenclature history )

Gene Function:
ubiquitin-protein ligase

Protein Function :
The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein ...[+]



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-977709 XB-GENE-977715 XB-GENE-17342952
Gene Symbol uba2 uba2.L uba2.S
Chromosome Chr04 chr4L Scaffold25
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 549845
399235
108704086
mRNA RefSeq RefSeq NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. NCBI Protein NCBI Protein  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine uba2 uba2.L uba2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards UBA2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Uba2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Uba2 Ensembl
zebrafish
ZFIN, AGR uba2 ZFIN Ensembl
chicken
GEISHA UBA2 Ensembl
fruit fly
FLYBASE Uba2 Ensembl
worm
Publications
First Conservation and divergence of protein pathways in the vertebrate heart., PLoS Biol 2019                                                      
Most Recent
All View All Papers 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 10 terms 7 terms 0 term
PANTHER uba2
KEGG Pathways K10685 K10685
KOG [O] SMT3/SUMO-activating complex, catalytic component UBA2
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks uba2
ORFs uba2 ORF1 uba2.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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