Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (29) GO Terms (24) Nucleotides (187) Proteins (46) Interactants (518) Wiki
XB-GENEPAGE-978215
Gene Symbol:
dusp6

Gene Name:
dual specificity phosphatase 6

Synonyms:
MAP kinase phosphatase , mkp3 , pyst1 , X17C ( Add synonyms , Nomenclature history )

Gene Function:
MAP kinase phosphatase

Protein Function :


InterPro :
TYR PHOSPHATASE DUAL dom , Rhodanese-like dom sf , MKP , Rhodanese-like dom [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
hypogonadotropic hypogonadism [+]

OMIM:
HYPOGONADOTROPIC HYPOGONADISM 7 WITH OR WITHOUT ANOSMIA; HH7 [+]

External Links:
1/4
 
Xenbase Gene ID XB-GENE-978216 XB-GENE-978223 XB-GENE-17333168
Gene Symbol dusp6 dusp6.L dusp6.S
Chromosome Chr3 chr3L chr3S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 733815
398829
495060
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine dusp6 dusp6.L dusp6.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards DUSP6 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Dusp6 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Dusp6 Ensembl
zebrafish
ZFIN, AGR dusp6 ZFIN Ensembl
chicken
GEISHA DUSP6 Ensembl
fruit fly
worm
Publications
First The CL100 gene, which encodes a dual specificity (Tyr/Thr) MAP kinase phosphatase, is highly conserved and maps to human chromosome 5q34., Hum Genet 1994  
Most Recent Developmental regulation of Wnt signaling by Nagk and the UDP-GlcNAc salvage pathway., Mech Dev 2019                                
All View All Papers 2 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 23 terms 3 terms 2 terms
PANTHER dusp6
KEGG Pathways K04459 [+] K21946 [+] K21946 [+]
KOG [V] Dual specificity phosphatase (alt_id KOG:1717)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks dusp6
Morpholinos (on-target & off-target) dusp6 MO1 dusp6 MO1 dusp6 MO1
ORFs dusp6 ORF1 , dusp6 ORF2 dusp6.L ORF1 LOC495060 ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info