Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (80) GO Terms (21) Nucleotides (736) Proteins (60) Interactants (501) Wiki
XB-GENEPAGE-979093
Gene Symbol:
rcc1

Gene Name:
regulator of chromosome condensation 1

Synonyms:
xrcc1 , RanGEF , chc1 , rcc1-a , rcc1-b ( Add synonyms , Nomenclature history )

Gene Function:
Uncharacterized conserved protein, contains RCC1 domain

Protein Function :
Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP, and thereby plays an important role in RAN-mediated functions in nuclear import and mitosis. Contributes to the g...[+]



Interactants:
Loading ...

Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-979094 XB-GENE-6252622 XB-GENE-979099
Gene Symbol rcc1 rcc1.L rcc1.S
Chromosome Chr02 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 548855
397722
443810
mRNA RefSeq RefSeq RefSeq
Protein RefSeq RefSeq Swiss-Prot RefSeq
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine rcc1 rcc1.L rcc1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards RCC1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Rcc1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Rcc1 Ensembl
zebrafish
ZFIN, AGR rcc1 ZFIN Ensembl
chicken
GEISHA RCC1 Ensembl
fruit fly
FLYBASE Rcc1 Ensembl
worm
Publications
First Cloning of Xenopus RCC1 cDNA, a homolog of the human RCC1 gene: complementation of tsBN2 mutation and identification of the product., J Biochem 1990  
Most Recent Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L., Cell 2019                                
All View All Papers 2 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 16 terms 6 terms 0 term
PANTHER rcc1
KEGG Pathways K11493 K11493 K11493
KOG [S] Uncharacterized conserved protein, contains RCC1 domain
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks rcc1
Morpholinos rcc1 MO1 rcc1 MO1 rcc1 MO1
ORFs rcc1.L ORF1 rcc1.S ORF1 , rcc1.S ORF2
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.14.0
Major funding for Xenbase is provided by grant P41 HD064556