Gene Symbol: ube2e3 Gene Name: ubiquitin-conjugating enzyme E2E 3 Synonyms: ubch9, ubcm2, xubc15, ubc15 Add Xenopus synonyms Gene Function: ubiquitin-protein ligase Interactants: nedd4(1) , nedd4l(1) , View All

Molecules		tropicalis	laevis a		laevis b
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene		Entrez Gene
mRNA		Refseq >NM_203974|Xenopus (Silurana) tropicalis ubiquitin-conjugating enzyme E2E 3 (ube2e3), mRNA GTTCGGCAGCCGGCCGGAGCCTGCTCGTTTCCCCGGCTCTGCGTTCCCAGGATCTCCCGGCGGCAGCGGCACACACAGCGGCGTGAGGAGAGCAGGGACCGGCGCGCCCGGAAGATTGCATCCAGAAGAAACAGAATCCATCAAGATGTCTAGTGATAGACAGCGCTCAGATGATGAAAGCCCTAGTACCAGTAGTGGAAGTTCAGATGCTGACCAGCGAGACCCACCAGCACCAGAACCTGAAGAGCAAGAAGAAAGAAAACCCTCGGCGGTCCAACAAAAGAAAAATACCAAACTGTCCAGTAAAACCACTGCTAAGCTGTCCACTAGTGCTAAAAGGATTCAGAAGGAGTTGGCTGAAATAACCCTTGATCCTCCTCCGAACTGCAGCGCTGGACCAAAGGGGGACAATATTTATGAATGGAGATCTACGATTCTTGGACCTCCAGGATCAGTATATGAGGGGGGTGTATTTTTCTTGGATATCACATTTTCATCTGATTATCCCTTTAAGCCACCAAAGGTCACTTTTCGCACCAGAATCTATCACTGTAATATTAACAGCCAGGGAGTAATCTGCTTGGATATTCTGAAAGATAACTGGAGTCCAGCATTGACTATATCAAAAGTTTTGCTATCTATTTGTTCCCTCTTGACAGACTGCAATCCCGCTGATCCACTGGTCGGAAGCATAGCCACTCAGTACCTGACCAACAGAGCCGAGCATGACAGGATAGCGAGACAGTGGACCAAGAGATATGCTACATAAACTGTACAGTGAAAAGCACAAGGCATCTGTACAATGTGCAACAAATCTTTATAGCCTTTACAATACGGACTTCTGTGTATATGTTATACTGATTCTACTCTCTGCTTTTATCCTATGAAGACTGGTATACTGCCCCAAAAGGTAAATACTAAGAAGAGTAGAACTTTGTAGCTGTAGATTAGTAATGTTAAAATGCCTACTTGCAAGTCTTGCTTCTTTGGGATATCAAAATGTATTTTGTGATGTACTAAGAATACTGTTCCAAACCAAATATTATAGTGCATTTTAGCCTAATTCATTATCTGTATGAGGTTATTAAAGTTAGCAGTAGATTACTAGAAATTGTCATTTGTATTAAACCCAGAAATATTTCCAATTATGTGGTAGACACTGTTGTGAAAACTGTTTTACCTTTTGTCAGTTTGAACTGAAAAGATTTCCTTTATTCCTTTGTAGCTCAGAGAGCACCCAAATGTATTATCCCAAACACACAATAAACATGTTCCCTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001096743|Xenopus laevis ubiquitin-conjugating enzyme E2E 3 (ube2e3-a), mRNA GGCCATTTTATTTTACAGACTGCGACAAGAGTTTAAACGAGGTTGAAAAGTAGAAACTTTACGGAAAGATTGCACCAAGAAGAAACAAAGTCCATCAACATGTCTAGTGATAGACAGCGGTCAGATGATGAAAGTCCTAGTACCAGCAGTGGAAGTTCAGATGCTGATCAGCGAGACCCACCAGCACCAGAACCTGAAGAACAAGAAGAAAGAAAGCCCTCGGCAGTCCAACAAAAGAAAAACACCAAACTGTCCAGTAAAACCACTGCTAAGCTGTCCACTAGTGCTAAAAGGATTCAGAAGGAGTTGGCTGAAATAACCCTTGATCCTCCTCCGAACTGCAGCGCTGGACCAAAGGGGGACAATATTTATGAATGGAGATCTACGATTCTTGGACCACCAGGATCCGTATATGAGGGGGGTGTATTTTTTTTGGATATCACATTTTCATCTGATTATCCATTTAAGCCACCAAAGGTCACTTTTCGCACCAGAATCTATCACTGTAATATAAACAGCCAGGGTGTAATCTGCTTGGATATTCTGAAAGATAACTGGAGTCCAGCATTGACTATATCAAAAGTTTTGCTATCTATTTGTTCCCTCTTGACAGACTGCAATCCTGCTGATCCACTGGTCGGAAGCATAGCCACGCAGTATCTGACCAACAGAGCAGAGCATGACAGGATAGCGAGACAGTGGACCAAGAGATATGCTACATAAATTGTACAGTGTAAAGCACAAGGCATCTGTACAATGTGCGACAAATCTTTATAGCCTTTACAATACGGACTTCTGTGTATATGTTATACTGATTCTACTCTCTGCTTTTATCCTATGAAGACTGGTATACTGCCCCAAAAGGTAAATACTATGAAGAGTAGAACTTTGTAGCTGTAGATTAGTAACGTTAAAATGCCTACTTGCAAGTCTTGCTTCTTTGGGATATCAAAATGTATTTTGTGATGTACTAAGAATACTGTTCCAAACCAAATATTATAGTGCATTTTAGCCTAATTCATTATCTGTATGACGTTATTAAAGTTAGTAGATTACTAGAAATTGTCATTTGTATTAAACCCAGAAATATTTACAATTATGTGGTACACACTGTTGTGAAAACTGTTTTACCTTTGTCAGTTTGAACTGAAAAGATTTCCTTTATTCCTTTGTAGCTCAGAGAGCACCCAAATGTATTATCCCAAACACAAAATAAACATGTTCCCTAAAAAAAAAAAAAAA		Refseq >NM_001090961|Xenopus laevis ubiquitin-conjugating enzyme E2E 3 (ube2e3-b), mRNA ACCTCCTCCTCTTTTCTTCCGACTCTCAATGTTCGGCAGCCGGCCGGAGCCTGCTTGTTTCCCCGGCTCTGCGTTCCCAGGATCCCCCCTCCCGGACAGCACCACACAGAGCGGCGGTGGAGTGAGGAGAGCAGGGACCGGCGCGCCCGAGAGATTGCATCAAGAAGATCCAAAGTCCATCAAGATGTCTAGTGATAGACAGCGGTCAGATGATGAAAGTCCTAGTACCAGTAGTGGAAGTTCAGATGCTGATCAGCGAGACCCACCAGCACCAGAACCCGAAGAACAAGAAGAAAGAAAACCCTCAGCAGTCCAACAAAAGAAAAATACCAAACTGTCCAGCAAAACCACTGCTAAGCTGTCCACTAGCGCTAAAAGGATTCAGAAGGAGTTGGCTGATATAACCCTTGATCCTCCTCCGAACTGCAGTGCTGGGCCAAAGGGCGACAATATTTATGAATGGAGATCTACAATTCTTGGTCCTCCAGGATCAGTATATGAAGGGGGCGTATTTTTTTTGGATATCACATTTTCATCTGATTATCCATTTAAGCCACCAAAGGTCACTTTTCGCACCAGAATCTATCACTGTAATATAAACAGCCAGGGTGTAATCTGCTTGGATATTCTGAAAGATAACTGGAGTCCAGCATTGACTATATCAAAAGTTTTGCTATCTATTTGTTCCCTCTTGACAGACTGCAATCCTGCTGATCCACTGGTCGGAAGCATAGCCACGCAGTATCTGACCAACAGAGCAGAGCATGACAGGATAGCGAGACAGTGGACCAAGAGATATGCTACATAAACTGTACAGCGTAAAGCACAAGGCATCTGTACAATGTGCAACAAATCTTTATAGCCTTTACAATACGGACTTCTGTGTATATGTTATACTGATTCTACTCTCCGCTTTTATCCTATGAAGACTGGTATACTGCCCCGAATGGTAAATACTAT
Protein		Refseq >NP_989305|ubiquitin-conjugating enzyme E2E 3 [Xenopus (Silurana) tropicalis] MSSDRQRSDDESPSTSSGSSDADQRDPPAPEPEEQEERKPSAVQQKKNTKLSSKTTAKLSTSAKRIQKELAEITLDPPPNCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFSSDYPFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYLTNRAEHDRIARQWTKRYAT	Refseq >NP_001090212|ubiquitin-conjugating enzyme E2E 3 [Xenopus laevis] MSSDRQRSDDESPSTSSGSSDADQRDPPAPEPEEQEERKPSAVQQKKNTKLSSKTTAKLSTSAKRIQKELAEITLDPPPNCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFSSDYPFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYLTNRAEHDRIARQWTKRYAT		Refseq >NP_001084430|ubiquitin-conjugating enzyme E2E 3 [Xenopus laevis] MFGSRPEPACFPGSAFPGSPLPDSTTQSGGGVRRAGTGAPERLHQEDPKSIKMSSDRQRSDDESPSTSSGSSDADQRDPPAPEPEEQEERKPSAVQQKKNTKLSSKTTAKLSTSAKRIQKELADITLDPPPNCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFSSDYPFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYLTNRAEHDRIARQWTKRYAT

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis a		laevis b
UniGene		Str.1758	Xl.7787		Xl.85503
Unigene EST Profile		EST Profile	EST Profile		EST Profile
GEO data			GEO		GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	UBE2E3
mouse		MGI	Ube2e3	All(1) Gene Trapped(1)
zebrafish		ZFIN	ube2e3	1 Lines(s)

Publications
First:		Participation of the ubiquitin-conjugating enzyme UBE2E3 in Nedd4-2-dependent regulation of the epithelial Na+ channel. [Mol Cell Biol 2004]
Most recent:
		View All Papers

Functional Ontologies
GO: Molecular:		ubiquitin conjugating enzyme activity ubiquitin-protein ligase activity
Biological:		protein modification process ubiquitin cycle
Cellular Component:
EC:		ubiquitinprotein ligase
KOG:		[O] Ubiquitin-protein ligase (alt_id KOG:0417)

Reagents		tropicalis	laevis a		laevis b
Clones		open biosystems	open biosystems		open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes		geneservice/RZPD imagenes
Affymetrix 1.0		Str.1758.1.S1_at			Xl.7787.1.S1_at
Affymetrix 2.0			Xl2.7787.1.S1_at

Symbol legend[+]

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