Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (13) GO Terms (19) Nucleotides (112) Proteins (32) Interactants (169) Wiki
XB-GENEPAGE-982077
Gene Symbol:
exo1

Gene Name:
exonuclease 1

Synonyms:
Xexo1 ( Add synonyms , Nomenclature history )

Gene Function:
5'-3' exonuclease

Protein Function :
5' double-stranded DNA exonuclease activity. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounte...[+]



Interactants:
Loading ...

Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-982078 XB-GENE-17330227 XB-GENE-982081
Gene Symbol exo1 exo1.L exo1.S
Chromosome Chr08 chr8S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 100487930
399140
mRNA NCBI Nucleotide RefSeq
Protein NCBI Protein RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine exo1 exo1.L exo1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards EXO1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Exo1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Exo1 Ensembl
zebrafish
ZFIN, AGR exo1 ZFIN Ensembl
chicken
GEISHA EXO1 Ensembl
fruit fly
worm
Publications
First Mechanistic analysis of Xenopus EXO1''s function in 5''-strand resection at DNA double-strand breaks., Nucleic Acids Res 2011                  
Most Recent Dna2 initiates resection at clean DNA double-strand breaks., Nucleic Acids Res 2017              
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 17 terms 0 term 7 terms
PANTHER exo1
KEGG Pathways K10746 K10746
KOG [L] 5'-3' exonuclease
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks exo1
ORFs exo1.S ORF1
Clones Horizon Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.15.0
Major funding for Xenbase is provided by grant P41 HD064556