Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (1) Nucleotides (153) Proteins (16) Interactants (3) Wiki
XB-GENEPAGE- 983639

Gene Symbol: tk2

Gene Name: thymidine kinase 2, mitochondrial

Synonyms:
Add Xenopus synonyms , Nomenclature history

Gene Function: Mitochondrial thymidine kinase 2/deoxyguanosine kinase

Interactants: dck.1 (1) , dck.2 (1) , dguok (1) , tk1 (1) , View All

OMIM Disease Associations: MITOCHONDRIAL DNA DEPLETION SYNDROME 3 (HEPATOCEREBRAL TYPE)... [+]
 
Xenbase Gene ID XB-GENE-983640 XB-GENE-17346102 XB-GENE-983645
Gene Symbol tk2 tk2.L tk2.S
Chromosome: Chr04 chr4S
Molecules tropicalis laevis .L laevis.S
Gene GBrowse 8.0 GBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 GBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq Refseq
Genomic tropicalis laevis .L laevis.S
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis .L laevis.S
Ensembl Ensembl
UniGene Str.424 [+] Xl.2832 [+]
RNA-seq profile: Owens, Blitz et al. 2016 tk2
Images 0 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis .L laevis.S
XenMine tk2 tk2.L tk2.S
Phenotype tropicalis laevis .L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards TK2 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Tk2 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN tk2 ZFIN Ensembl
chicken
GEISHA TK2 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Deoxyribonucleoside kinases belonging to the thymidine kinase 2 (TK2)-like group vary significantly in substrate specificity, kinetics and feed-back regulation. [J Mol Biol 2002]
Most recent:
View All Papers
Functional Ontologies
GO: Molecular: ATP binding   phosphotransferase activity, alcohol group as acceptor   thymidine kinase activity  
      Biological: nucleobase-containing compound metabolic process  
      Cellular Component:
EC: thymidine kinase
PANTHER: tk2
KOG: [F] Mitochondrial thymidine kinase 2/deoxyguanosine kinase
Reagents tropicalis laevis .L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
geneservice/RZPD imagenes geneservice/RZPD imagenes
Affymetrix 1.0 Str.424.1.S1_at [+] Xl.2832.1.S1_at [+]
Affymetrix 2.0 Xl2.2832.1.S1_at [+]

Symbol legend[+]

My Xenbase: [ Log-in / Register ]
version: [4.1.1]

Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556