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Summary Expression Phenotypes Gene Literature (9) GO Terms (5) Nucleotides (82) Proteins (33) Interactants (66) Wiki
XB-GENEPAGE-988967
Gene Symbol :
apaf1

Gene Name :
apoptotic peptidase activating factor 1

Synonyms:
apaf-1 ( Add synonyms , Nomenclature history )

Gene Function:
apoptosis/apoptosome scaffold protein with WD-40 domains, caspase recruitment domain (CARD), and an ATPase domain

Protein Function :
Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.


Interactants:
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Diseases: 


External Links:
 
Expression                  Development Stages                                               Embryonic Tissuesd                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: Single cell: RNA-Seq:

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