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XB-GENEPAGE-991583
Gene Symbol:
kcna2
Gene Name: potassium channel, voltage gated shaker related subfamily A, member 2
Synonyms:
kv1.2
,
k(v)1.2
( Gene Function: Voltage-gated shaker-like K+ channel KCNA Protein Function
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Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and central nervous system. Prevents aberrant action potential firing and ...[+]
Interactants:
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Diseases: Disease Ontology:
developmental and epileptic encephalopathy 32
OMIM:
DEVELOPMENTAL AND EPILEPTIC ENCEPHALOPATHY 32; DEE32
External Links:
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Xenbase Gene ID | XB-GENE-991578 | XB-GENE-991585 | XB-GENE-17341622 | |||||
Gene Symbol | kcna2 | kcna2.L | kcna2.S | Chromosome | Chr2 | chr2L | chr2S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.2
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Version 9.2
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CDS |
Gene model
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Gene model
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Gene model
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Entrez Gene |
100496794
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373840
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108709388
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mRNA |
NCBI Nucleotide
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NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | kcna2 | kcna2.L | kcna2.S | |||||
Orthology |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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worm |
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Publications | ||||||||
First |
Effects of the level of mRNA expression on biophysical properties, sensitivity to neurotoxins, and regulation of the brain delayed-rectifier K+ channels Kv1.2., Biochemistry 1992 |
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Most Recent |
Isoform-Selective KCNA1 Potassium Channel Openers Built from Glycine., J Pharmacol Exp Ther 2020 |
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All | View All Papers 2 paper(s) referencing OMIMs 4 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 17 terms | 9 terms | 4 terms | |||||
PANTHER | kcna2 | |||||||
KEGG Pathways | K00069 [+] | K04875 | K04875 | |||||
KOG |
[P] Voltage-gated shaker-like K+ channel KCNA
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | kcna2 | |||||||
Antibodies | Kcna3 Ab1 | Kcna2 Ab1 | ||||||
Clones | Horizon | EXRC Horizon Source BioScience | Horizon | |||||
Plasmids | Addgene | Addgene |
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