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Summary Expression Gene Literature (16) GO Terms (17) Nucleotides (146) Proteins (44) Interactants (358) Wiki
XB-GENEPAGE-991894
Gene Symbol:
abcg2

Gene Name:
ATP binding cassette subfamily G member 2 (Junior blood group)

Synonyms:
bcrp ( Add synonyms , Nomenclature history )

Gene Function:
White subfamily. Involved in cholesterol and phospholipid transport [Entrez]

Protein Function :
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP throug...[+]


InterPro :
ABC transporter-like , P-loop NTPase , AAA+ ATPase , ABCG2 [+]

Interactants:
Loading ...

Diseases: 


OMIM:
BLOOD GROUP, JUNIOR SYSTEM; JR [+]

External Links:
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Xenbase Gene ID XB-GENE-991895 XB-GENE-991900 XB-GENE-17335055
Gene Symbol abcg2 abcg2.L abcg2.S
Chromosome Chr1 chr1L chr1S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 734088
100036892
108706758
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein NCBI Protein  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine abcg2 abcg2.L abcg2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards ABCG2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Abcg2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Abcg2 Ensembl
zebrafish
chicken
GEISHA ABCG2 Ensembl
fruit fly
worm
Publications
First Functional characterization of human breast cancer resistance protein (BCRP, ABCG2) expressed in the oocytes of Xenopus laevis., Mol Pharmacol 2003  
Most Recent Dual actions on gout flare and acute kidney injury along with enhanced renal transporter activities by Yokuininto, a Kampo medicine., BMC Complement Altern Med 2019          
All View All Papers 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 17 terms 7 terms 7 terms
PANTHER abcg2
KEGG Pathways K05681 K05681
KOG [Q] Transporter, ABC superfamily (Breast cancer resistance protein)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks abcg2
Antibodies abcg2 Ab1 abcg2 Ab1 abcg2 Ab1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info