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Summary Expression Gene Literature (4) GO Terms (3) Nucleotides (33) Proteins (18) Interactants (101) Wiki
XB-GENEPAGE-994579
Gene Symbol:
tmprss3

Gene Name:
transmembrane serine protease 3

Synonyms:
dfnb8 , dfnb10 , echos1 , tadg12 ( Add synonyms , Nomenclature history )

Gene Function:
This gene encodes a protein that belongs to the serine protease family.

Protein Function :


Interactants:
Loading ...

Diseases: 


Disease Ontology:
autosomal recessive nonsyndromic deafness 8

OMIM:
DEAFNESS, AUTOSOMAL RECESSIVE 8; DFNB8

External Links:
 
Xenbase Gene ID XB-GENE-994580 XB-GENE-17330647 XB-GENE-17330648
Gene Symbol tmprss3 tmprss3.L tmprss3.S
Chromosome Chr02 chr2L
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 100490444
108707842
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine tmprss3 tmprss3.L tmprss3.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards TMPRSS3 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Tmprss3 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Tmprss3 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR tmprss3a tmprss3b ZFIN Ensembl
chicken
GEISHA TMPRSS3 Ensembl
fruit fly
worm
Publications
First The transmembrane serine protease (TMPRSS3) mutated in deafness DFNB8/10 activates the epithelial sodium channel (ENaC) in vitro., Hum Mol Genet 2002  
Most Recent Novel Mutations in the TMPRSS3 Gene may Contribute to Taiwanese Patients with Nonsyndromic Hearing Loss., Int J Mol Sci 2020                
All View All Papers 2 paper(s) referencing OMIMs 3 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 0 term 3 terms 0 term
PANTHER tmprss3
KEGG Pathways K09634
KOG [E] Trypsin
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks tmprss3
Clones Horizon Horizon

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