Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (2) GO Terms (11) Nucleotides (140) Proteins (23) Interactants (18) Wiki
XB-GENEPAGE-995305
Gene Symbol:
ephx1

Gene Name:
epoxide hydrolase 1, microsomal (xenobiotic)

Synonyms:
meh , ephx , epox , epoxide hydrolase ( Add synonyms , Nomenclature history )

Gene Function:
Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Protein Function :
Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water.



Interactants:
Loading ...

Diseases: 


Disease Ontology:
pre-eclampsia

OMIM:
HYPERCHOLANEMIA, FAMILIAL; FHCA [+]

External Links:
1/2
 
Xenbase Gene ID XB-GENE-995306 XB-GENE-995309 XB-GENE-17337761
Gene Symbol ephx1 ephx1.L ephx1.S
Chromosome Chr05 chr5L
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 100158543
432100
mRNA RefSeq RefSeq
Protein RefSeq RefSeq
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine ephx1 ephx1.L ephx1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards EPHX1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Ephx1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Ephx1 Ensembl
zebrafish
ZFIN, AGR ephx5 ZFIN Ensembl
chicken
GEISHA EPHX1 Ensembl
fruit fly
worm
Publications
First Relationship between the microsomal epoxide hydrolase and the hepatocellular transport of bile acids and xenobiotics., Biochem J 1995  
Most Recent Isolation and characterization of Xenopus soluble epoxide hydrolase., Biochim Biophys Acta 2014                      
All View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 11 terms 4 terms 0 term
PANTHER ephx1
KEGG Pathways K01253 K01253
KOG [R] Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks ephx1
ORFs ephx1.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.14.0
Major funding for Xenbase is provided by grant P41 HD064556