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Summary Expression Gene Literature (11) GO Terms (11) Nucleotides (213) Proteins (38) Interactants (466) Wiki
XB-GENEPAGE-996356
Gene Symbol:
crk

Gene Name:
v-crk avian sarcoma virus CT10 oncogene homolog

Synonyms:
v-crk , crkII ( Add synonyms , Nomenclature history )

Gene Function:
Crk family adapters

Protein Function :
Required for apoptosis in Xenopus egg extracts (PubMed:9029144). Involved in cell branching and adhesion. May mediate attachment-induced mapk8 activation, membrane ruffling and cell motility in a Rac-d...[+]



Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-996357 XB-GENE-996363 XB-GENE-17333219
Gene Symbol crk crk.L crk.S
Chromosome Chr02 chr2L chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 448023
398951
108709342
mRNA RefSeq RefSeq NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein NCBI Protein  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine crk crk.L crk.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards CRK OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Crk MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Crk Ensembl
zebrafish
ZFIN, AGR crk ZFIN Ensembl
chicken
GEISHA CRK Ensembl
fruit fly
FLYBASE FLYBASE Crk crooked-setae Ensembl
worm
Publications
First Crk is required for apoptosis in Xenopus egg extracts., EMBO J 1997  
Most Recent Similarity in gene-regulatory networks suggests that cancer cells share characteristics of embryonic neural cells., J Biol Chem 2017          
All View All Papers 1 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 6 terms 5 terms 0 term
PANTHER crk
KEGG Pathways K04438 K04438 K04438
KOG [T] Crk family adapters
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks crk
Antibodies Crk Ab1
ORFs crk ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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