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Summary Expression Gene Literature (20) GO Terms (26) Nucleotides (258) Proteins (54) Interactants (341) Wiki
XB-GENEPAGE-1000631
Gene Symbol:
dctn2

Gene Name:
dynactin subunit 2

Synonyms:
rbp50 , dctn50 , dynamitin , dctn2-a , dctn2-b ( Add synonyms , Nomenclature history )

Gene Function:
Putative dynamitin

Protein Function :
Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. M...[+]



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-1000632 XB-GENE-1000638 XB-GENE-6256553
Gene Symbol dctn2 dctn2.L dctn2.S
Chromosome Chr02 chr2L chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 548423
447510
380299
mRNA RefSeq RefSeq RefSeq
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine dctn2 dctn2.L dctn2.S
Phenotype X. tropicalis X. laevis.L X. laevis.S
Smith Morpholino Screen tegg139n15      
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards DCTN2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Dctn2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Dctn2 Ensembl
zebrafish
ZFIN, AGR dctn2 ZFIN Ensembl
chicken
GEISHA DCTN2 Ensembl
fruit fly
worm
Publications
First Recombinant p50/dynamitin as a tool to examine the role of dynactin in intracellular processes., Methods Cell Biol 1999  
Most Recent Dynein-Based Accumulation of Membranes Regulates Nuclear Expansion in Xenopus laevis Egg Extracts., Dev Cell 2015                
All View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 25 terms 9 terms 10 terms
PANTHER dctn2
KEGG Pathways K10424 K10424 K10424
KOG [Z] Putative dynamitin
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks dctn2
Morpholinos dctn2 MO1 , dctn2 MO2 dctn2 MO1 , dctn2 MO2 dctn2 MO1 , dctn2 MO2
ORFs dctn2 ORF1 dctn2.L ORF1 dctn2.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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