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Summary Expression Gene Literature (10) GO Terms (18) Nucleotides (90) Proteins (32) Interactants (114) Wiki
Gene Symbol:

Gene Name:
eukaryotic translation initiation factor 2 alpha kinase 2

pkr , prkr , eif2ak1 , pkr1 ( Add synonyms , Nomenclature history )

Gene Function:
eIF-2alpha kinase PEK/EIF2AK3

Protein Function :

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External Links:
Xenbase Gene ID XB-GENE-1001011 XB-GENE-1001017 XB-GENE-17334423
Gene Symbol eif2ak2 eif2ak2.L eif2ak2.S
Chromosome Chr5 chr5L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 779992
mRNA RefSeq NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine eif2ak2 eif2ak2.L eif2ak2.S
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
HGNC, AGR, Monarch, OMIM, GeneCards EIF2AK2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
MGI, AGR Eif2ak2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
RGD, AGR Eif2ak2 Ensembl
ZFIN, AGR eif2ak2 ZFIN Ensembl
fruit fly
First Oncogenic potential of TAR RNA binding protein TRBP and its regulatory interaction with RNA-dependent protein kinase PKR., EMBO J 1997  
Most Recent Noncanonical Modulation of the eIF2 Pathway Controls an Increase in Local Translation during Neural Wiring., Mol Cell 2019                  
All View All Papers 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 18 terms 12 terms 0 term
PANTHER eif2ak2
KEGG Pathways K16195 K16195
KOG [J] eIF-2alpha kinase PEK/EIF2AK3
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks eif2ak2
Clones Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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