Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (2) GO Terms (9) Nucleotides (156) Proteins (48) Interactants (124) Wiki
XB-GENEPAGE-1003309
Gene Symbol:
spop

Gene Name:
speckle type POZ protein

Synonyms:
tef2 , spop-a , spop-b ( Add synonyms , Nomenclature history )

Gene Function:
Speckle-type POZ protein SPOP and related proteins with TRAF, MATH and BTB/POZ domains

Protein Function :
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation.



Interactants:
Loading ...

Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-1003310 XB-GENE-6254679 XB-GENE-1003315
Gene Symbol spop spop.L spop.S
Chromosome Chr10 chr9_10L chr9_10S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 394599
379868
779391
mRNA RefSeq RefSeq RefSeq
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine spop spop.L spop.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SPOP OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Spop MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Spop Ensembl
zebrafish
ZFIN, AGR spop ZFIN Ensembl
chicken
GEISHA SPOP Ensembl
fruit fly
worm
Publications
First Stabilization of speckle-type POZ protein (Spop) by Daz interacting protein 1 (Dzip1) is essential for Gli turnover and the proper output of Hedgehog signaling., J Biol Chem 2013                  
Most Recent CPEB4 is regulated during cell cycle by ERK2/Cdk1-mediated phosphorylation and its assembly into liquid-like droplets., Elife 2016                                              
All View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 9 terms 5 terms 5 terms
PANTHER spop
KEGG Pathways K10523 K10523 K10523
KOG [DR] Speckle-type POZ protein SPOP and related proteins with TRAF, MATH and BTB/POZ domains
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks spop
Antibodies Spop AB1 Spop AB1 Spop AB1
ORFs spop ORF1 spop.L ORF1 spop.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.15.0
Major funding for Xenbase is provided by grant P41 HD064556