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Summary Expression Gene Literature (11) GO Terms (29) Nucleotides (73) Proteins (39) Interactants (33) Wiki
XB-GENEPAGE-1005778
Gene Symbol:
drd2

Gene Name:
dopamine receptor D2

Synonyms:
d2r , d2dr , drd2-a , drd2-b ( Add synonyms , Nomenclature history )

Gene Function:
Muscarinic acetylcholine receptor

Protein Function :
This is one of the five types (D1 to D5) of receptors for dopamine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. In Xenopus D2R is involved in the regulation...[+]



Interactants:
Loading ...

Diseases: 


Disease Ontology:
myoclonic dystonia 11

OMIM:
DYSTONIA 11, MYOCLONIC; DYT11

External Links:
 
Xenbase Gene ID XB-GENE-1005779 XB-GENE-1005782 XB-GENE-6252634
Gene Symbol drd2 drd2.L drd2.S
Chromosome Chr7 chr7L chr7S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100493063
378584
378597
mRNA NCBI Nucleotide RefSeq NCBI Nucleotide
Protein NCBI Protein RefSeq Swiss-Prot  More.. NCBI Protein NCBI Protein  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine drd2 drd2.L drd2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards DRD2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Drd2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Drd2 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR drd2b drd2a ZFIN Ensembl
chicken
GEISHA DRD2 Ensembl
fruit fly
worm
Publications
First Functional expression and characterization of human D2 and D3 dopamine receptors., J Neurosci 1994  
Most Recent Ligand with Two Modes of Interaction with the Dopamine D2 Receptor-An Induced-Fit Mechanism of Insurmountable Antagonism., ACS Chem Neurosci 2020              
All View All Papers 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 24 terms 7 terms 7 terms
PANTHER drd2
KEGG Pathways K04145
KOG [T] Muscarinic acetylcholine receptor
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks drd2
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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