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Summary Expression Gene Literature (39) GO Terms (11) Nucleotides (151) Proteins (29) Interactants (215) Wiki
XB-GENEPAGE-1010856
Gene Symbol:
bub1b

Gene Name:
BUB1B, mitotic checkpoint serine/threonine kinase

Synonyms:
bubr1 ( Add synonyms , Nomenclature history )

Gene Function:
Mitotic checkpoint serine/threonine protein kinase

Protein Function :
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.



Interactants:
Loading ...

Diseases: 


Disease Ontology:
mosaic variegated aneuploidy syndrome 1 [+]

OMIM:
COLORECTAL CANCER; CRC [+]

External Links:
 
Xenbase Gene ID XB-GENE-1010857 XB-GENE-1010862 XB-GENE-17342314
Gene Symbol bub1b bub1b.L bub1b.S
Chromosome Chr08 chr8L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 100125106
378923
mRNA NCBI Nucleotide RefSeq
Protein NCBI Protein NCBI Protein NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine bub1b bub1b.L bub1b.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards BUB1B OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Bub1b MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Bub1b Ensembl
zebrafish
chicken
GEISHA BUB1B Ensembl
fruit fly
worm
Publications
First CENP-E as an essential component of the mitotic checkpoint in vitro., Cell 2000  
Most Recent Chromosome alignment maintenance requires the MAP RECQL4, mutated in the Rothmund-Thomson syndrome., Life Sci Alliance 2019                          
All View All Papers 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 11 terms 3 terms 0 term
PANTHER bub1b
KEGG Pathways K06637
KOG [D] Mitotic checkpoint serine/threonine protein kinase
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks bub1b
ORFs bub1b ORF1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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