Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (1) GO Terms (7) Nucleotides (132) Proteins (35) Interactants (100) Wiki
XB-GENEPAGE-1013024
Gene Symbol:
enpp4

Gene Name:
ectonucleotide pyrophosphatase/phosphodiesterase 4

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
Type I phosphodiesterase/nucleotide pyrophosphatase

Protein Function :
Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoa...[+]



Interactants:
Loading ...

Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-1013025 XB-GENE-1013030 XB-GENE-17346205
Gene Symbol enpp4 enpp4.L enpp4.S
Chromosome Chr5 chr5L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 550082
447221
mRNA NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine enpp4 enpp4.L enpp4.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards ENPP4 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Enpp4 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Enpp4 Ensembl
zebrafish
ZFIN, AGR enpp4 ZFIN Ensembl
chicken
GEISHA ENPP4 Ensembl
fruit fly
worm
Publications
First Ectophosphodiesterase/nucleotide phosphohydrolase (Enpp) nucleotidases: cloning, conservation and developmental restriction., Int J Dev Biol 2010                          
Most Recent
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 7 terms 6 terms 0 term
PANTHER enpp4
KEGG Pathways K18424 K18424
KOG [R] Type I phosphodiesterase/nucleotide pyrophosphatase
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks enpp4
ORFs enpp4 ORF1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info