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Summary Expression Gene Literature (11) GO Terms (21) Nucleotides (86) Proteins (24) Interactants (134) Wiki
XB-GENEPAGE-1014183
Gene Symbol:
kpna1

Gene Name:
karyopherin alpha 1

Synonyms:
rch2 , srp1 , ipoa5 , npi-1 , importin alpha-1 ( Add synonyms , Nomenclature history )

Gene Function:
Karyopherin (importin) alpha

Protein Function :
Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it b...[+]



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-1014184 XB-GENE-17333075 XB-GENE-6487922
Gene Symbol kpna1 kpna1.L kpna1.S
Chromosome scaffold_327 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 394800
108707813
108709282
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq NCBI Protein NCBI Protein
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine kpna1 kpna1.L kpna1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards KPNA1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Kpna1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Kpna1 Ensembl
zebrafish
ZFIN, AGR kpna1 ZFIN Ensembl
chicken
GEISHA KPNA1 Ensembl
fruit fly
worm
Publications
First Isolation of a yeast protein kinase that is activated by the protein encoded by SRP1 (Srp1p) and phosphorylates Srp1p complexed with nuclear localization signal peptides., Proc Natl Acad Sci U S A 1995  
Most Recent Altering the levels of nuclear import factors in early Xenopus laevis embryos affects later development., PLoS One 2019          
All View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 21 terms 4 terms 4 terms
PANTHER kpna1
KEGG Pathways K15042 K15042 K15042
KOG [U] Karyopherin (importin) alpha
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks kpna1
ORFs kpna1 ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience

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