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Summary Expression Gene Literature (18) GO Terms (9) Nucleotides (167) Proteins (66) Interactants (162) Wiki
XB-GENEPAGE-1015390
Gene Symbol:
mcm10

Gene Name:
minichromosome maintenance 10 replication initiation factor

Synonyms:
xmcm10 ( Add synonyms , Nomenclature history )

Gene Function:
Protein required for S-phase initiation or completion

Protein Function :
Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication. Additionally, plays a role in prevent...[+]



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-1015391 XB-GENE-1015396 XB-GENE-17344845
Gene Symbol mcm10 mcm10.L mcm10.S
Chromosome Chr03 chr3L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 549663
398196
mRNA RefSeq RefSeq
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine mcm10 mcm10.L mcm10.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards MCM10 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Mcm10 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Mcm10 Ensembl
zebrafish
ZFIN, AGR mcm10 ZFIN Ensembl
chicken
GEISHA MCM10 Ensembl
fruit fly
FLYBASE Mcm10 Ensembl
worm
Publications
First Xenopus Mcm10 binds to origins of DNA replication after Mcm2-7 and stimulates origin binding of Cdc45., Mol Cell 2002  
Most Recent The anti-parasitic agent suramin and several of its analogues are inhibitors of the DNA binding protein Mcm10., Open Biol 2019          
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 8 terms 7 terms 0 term
PANTHER mcm10
KEGG Pathways K10736 K10736
KOG [D] Protein required for S-phase initiation or completion
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks mcm10
ORFs mcm10.L ORF1 , mcm10.L ORF2
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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