dag1 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (20)

Nucleotides (170)

Interactants (26)

XB-GENEPAGE-1015768

Gene Symbol: dag1 Gene Name: dystroglycan 1 (dystrophin-associated glycoprotein 1) Synonyms: dystroglycan Add Xenopus synonyms Gene Function: laminin receptor Interactants: dmd.2(9) , dmd.1(8) , fn1(3) , hspg2(2) , utrn(2) , Agrn Ab1(1) , Dag1 Ab1(1) View All	1/4

XB-GENE-1015769

XB-GENE-1015774

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001016518\|Xenopus (Silurana) tropicalis dystroglycan 1 (dystrophin-associated glycoprotein 1) (dag1), mRNA CTGAGCGGCCTCTCGGGAGCGGCAGGAAAAGACCGGGAGTTATATGCCTCTTTTTCTTCGTATGTTGCCTGCCGCAAATAAAGGGAAATACCTGGCCACAAGATAGGACACAGAAACACACGGCAAATGTCCGTAATGAAGGAACACCGTGACCACTAAGACCAGACGAGCTGCTTCCTACGCTGAAACAGAACACCAAAATGGATATTAGGTGTGCTGCACTTTCCCTTCCCATGCTGAGGACTATAATGGTGCTGCTTATGGCTTCTTCCGCTTGGTCAGTCTGGCCTAGCGATCCAATGGAAGTTGTTCAGGACTGGGACAATCAGCTAGAGGCCTCCATGCATTCGCTGTTCCCTGAAATTAAAGAGGCAGTGGCACCAATGACAGGAATTCCAGACAGTTCTGCTGTGGTTGGCAGGCCCTTTAAAATCCACATCCCCACAGAATTTCTCGCTTCCAGTGGAGAAACAATCAAGATTTTTGAAGTTGGAAAGGAGATTTTGCCATCTTGGTTACACTGGGAAGCTAATTTTTTGCAAGGTCTTCCCCTTGATGGTGACAAAGGGGTCTATGACATTTCTGTAGCCTCCATGCGCCTGGCACCAAATGGAAGTTATGTAACCCAAACCGCAGATGTTTTCGCTGTAGAGGTTCATCCTGAGGACCACAATGAGCCTCAATCTGTGCGAGTGGCAGGACAGGAAACCGCTGAAGCAACTCCTTTTCTATGTGGCACCGATGAGCCAGTAACAATTCTGACTGTAATTTTGGATGCGGACTTGACAAAAATGACACCAAAGCAGAGAGTAGATCTTCTAAACAGAATGAGGGACTTCTCTGAGGTAGAACTTTATCATATGAAATTAGTCCCAGTTGTAAACAACAGACTGTTTGATATGTCTGCCTTCATGGCTGGGCCAGGAAATGCAAAAAAAGTAGTTGAAAATGGAGCCTTGCTATCATGGAAGCTTGGGTGTGGAATGGATCAGAACACTGTTCCAAACATCAGTTCTGTAGAGGTTCCTGCTAAAGAAGGCACAATGTCTGCCCAGCTTGGTTATCCTGTTGTAGGCTGGCACATTGCAAATAAAAAACCCCAAATGCCTAAGCGAATTAGAAGGCAAATATATGCCACACCAACGCCTGTTACTGCCATTGGACCACCTACTACAGCCATTCATGAGCCTCCAGAAAGAATTGTGCCAACTCCCACTTCTCCTGCAATTGCTCCTCCAACCGACACAACAGCTCCTCCAGTTCGAGAACCTATACCTCTTCCAGGAAAACCAACAGTTACAATAAGAACAAGGGGTGCTATTATTCACACTCCCACTCTTGGTCCAATCCACCCAACTAGGATAATAGAAACTACTAGCATAGTTCGCCCAACTATCACCAGGCACATTTTTGTAGAACCAACTGCTGCAGTTACACCTCCTTCTACCACTACAAAGAGGCCAAGAACCACAATGAAGCCGCCCACACCACCAACTACCGATTCTTCTACCACAACAACAAAGAAACCCACCAAAAAACCAAGGCCCAGACCCCCCAAGCCTCTTGCTACTACCAAAGCACCGTCCACAAAAGTTGAGACTACATCGCCAAGCCGTACACGTCCTTCTACCAGTGGAGTACCCAACACTGACCCTGAACTTAAAAATCATATTGATAAGGTTGTTGCATGGGTGGGTACCTATTTTGAAGTTAAAATTCCCCCTGACACATTTTATGATAAAGAAGATGGCACCACTGATAATCTCCAGCTCTCTTTGGCGCCAAGACAAAAGGCTGGCCTTGGAGAGAAGATGTGGGTAATGCTCAATAGCACTAGCCAGGTTATGTATGGAATGCCTGACTATACACACATTGGAGACCATGAGTATTACTTGAGAGCTGCAGACAAAGCAGGACGCACTGCGGTGGATGCTTTAGAAATCCAAGTCCGTAATCTGTTCCAAAAACAACCATCCACTGTTAAATTTCATGCAAAGTTCCACGGGGATCACAATGCTGTCATTAATGACATTAATAAGAAAATTCTGCTAGTCAAAAAGTTGGCTTTTGCTTTTGGTGATAGAAACAGTAGTTCTATTACTTTGCATAATATCACCAAAGGTTCTGTGGTCGTGGACTGGACAAACAATACTTTCCCTGTAGAACCGTGTCCAGTAGAGCAAGTAGAAGGTGTCGGCAAAAAGATCTACGATGAACGTGGCAGTCCTCGGCAACATTTTGTTAACGCAGTGGAGCCGGAATTTAAACTTTTAAATATTTCTTTATCGTTCTCGGGGAGCTGTAAGCATAAAAAATTCAGGTACATACCTATGAGAGCAGAGGAACCCATACCCACTGCAGTGGCACCAACCGTAGCTGTAGACAGAAACCTGGAGAAGAGAAGTGAGGATGATGTCTACCTTCACACTGTTATTCCTGCGGTGGTGGTGGCTGCCATTTTGTTAATTGCTGGCATCATTGCTATGATTTGTTACCGGAAGAAGAGGAAAGGCAAACTGACAATAGAGGATCAGGCAACTTTTATTAAGAAGGGTGTTCCAATTATTTTTGCTGATGAATTAGATGACTCCAAGCCTCCTCCTTCTTCCAGTATGCCACTGATTCTAAAGGAGGAAAAAGCTCCCCTTCCTCCTCCTGAGTATCCTAATCAGAATGTTCCAGAGACAATCCCCCTGAACCAAGACAGCTTGGGGGAGTACACACCTCTTAGGGATGAGGACCCCAATGCACCCCCTTATCAACCTCCCCCACCCTTCACAGCACCTATGGAAGGTAAAGGGTCACGCCCCAAAAACATGACCCCATACCGGTCACCACCCCCTTATGTACCTCCTTAACGAACAGTGTGCTGAGTGAGAGGAGAAAGGGGGCTGTGAGTTCCAAACCAGTGTTGTCCGAAGAGATTGATAGCCTGCAATCTGCTGTCGGGATAACAGGAAAACTCTGCTGTTCTAGGCAAAGAGTAAAGACCTGGAGACTTTTTATAGTAACTCCACATTATACATGCCTCCTTCACAGATTGTGGAAAATATGGGACATATGTCATTTGCCTAACGATTTTTTTCGTATTGGTATTCATACAGATGTGTGCTCCGTTCTAGATATTTAACAGATTGCAGGCTTTAAAGACACTAAAGAGGAAAGTGATTGGACGATATGTTCAGCACTGGGGTGGCCTTTTGTTTCTCTGCTGTTTGCCTTTAACACTAACTGTATTATTATTATTTTTTTTTCCTTTTATTTACGTGTGTCTAGAGCTTCAGGTCATAACAAAATGGTATGACGAAAGGTATCTTGGAAACGGAACATCAGAATTTTTACATTTTTACATTTACTCCTGTCTTCTTTCTATATAAAGGACAGCTATCTATACTTAAAAAAAAAAAAAAAAAA	Refseq >NM_001089011\|Xenopus laevis dystroglycan 1 (dystrophin-associated glycoprotein 1) (dag1), mRNA AGAGGAGGGGGGAGTGAAGGGAGTGAGCGGCGGCCTGTGACAGGAGCCGGAGTTACTAGCAGCTCGGGGCAGAGTGGCCTCTCGGGAGCGGCAGGAAAGGACCGGGAGTTATTTGCCTCTTCATATTTGTATGCTGCAGGGGACATATCTGGCCACAAGGAAGGACACAGACACATACACGGCAGATGTCTGTAATGGAGGAACACCGTGACGACTAAGACCAGACAAGCTGCCTCCTACGCTGTAACAGAACGCCAAAATGGATATTAGGTGTGCTGGACTTTCCCTTCCCATGCTGAGGACTATAATGGTGCTGCTTATGGCTTCTTGCGCTTGGTCAGCCTGGCCTAGCGATCCTACGGAAGTCGCTCAGGATTGGGACAATCAGCTAGAGGCCTCCATGCATTCGCTGTTCCCTGAAATCAAAGAGACAGTGGCACCAATGACAGGAATTCCGGACAGTTCTGCTTTGGTTGGCAGGCCCTTTAAAATCCACATCCCCACAGAATTTCTCGCTTCCAGTGGAGAAACAATCAAGATTTCTGAAGTTGGAAAGGAGACATTGCCCTCTTGGTTACATTGGGAAGGTAATTTTTTGCAAGGTCTTCCCCTTGATGGGGACAAAGGGGTCTATGACATTTCTGTGGCCTCCCTGCACCTGGCACCAAATGGAAGTTATGTACCACATACCACAGATGTTTTCTCTGTAGAGGTTCATCCTGAGGACCACAATGAACCTCAATCTGTGCGAGTGGCAGGACAGGAAACCGCTGAAGCAATTCCTTTTCTATGTGGCACTGATGAGCCAGTAACACTTTTGACTGTAATTTTGGATGCAGACTTGACAAAAATGACACCAAAGCAGAGAGTGGATCTTCTGAACAGAATGAGAGACTTCTCTGAGGTAGAACTTTTTCACATGAAGTTAGTCCCCGTTGTAAACAACAGACTGTTTGACATGTCTGCCTTCATGGCTGGGCCAGGAAATGCAAAGAAAGTAGTAGAAAATGGAGCCTTGCTGTCTTGGAAACTTGGGTGTGGAATGGATCAGAACACTGTTCCAAACATCAGTTCTGTTGAGGTTCCCGCTAAAGAAGGCACAATGTCTGCCCAACTAGGTTATCCTGTTGTAGGCTGGCACATTGCAAATAAAAAACCCCAAATGCCTAAGAGAATTAGAAGGCAAATATATGCTACACCAACCCCTGTTACTGCTATTGGACCACCTACTACAGCTATTCATGAGCCTCCAGAAAGAATTGTGCCAACTCCCACTTCTCCTGCAATTGCTCCTCCAACTGACACAACAGCTCCCCCAGTTCGAGAACCTATACCTCTTCCAGGAAAACCAACAGTTACAATTAGAACAAGGGGTGCTATTATACACACTCCCACCCTTGGTCCAATCCACCCAACGAGGATAATAGAAACTACTAGTATAGTTCGCCCAACAATGACCAGGCCCATTTATGTAGAACCAACTGCTGCAGTTACACCTCCTTCTACTACTACAAAGAGGCCAAGAGTGACCACAATGAAACCTGCCACACCACCAACTACAGATTCTTCTACCACAACAACAAAGAAACCCACCAGAAAACCAAGAACCCGACCCCCCAAGCCTCTTGCTACTACCAAAGCACCAGCCACAAAATTTGAGACTACATCATCGAGCCGTACCCGTACGTCTACCAGTGGGGTACCTAACACTGACCCCGAACTTAAAAATCATATTGATAAGGTTGTTGCATGGGTGGGTACCTACTTTGAGGTTAAAATTCCACCTGATACATTTTATGATAGAGAAGATGGTACCACTGATAATCTCCAGCTCACTTTGGTGCCACGAATAAAGGCAAGCGCTGGGGAGAAGATGTGGGTTATGCTCAATAGTACTAGCCAGGTTATGTATGGTATGCCTGACTATATACATATTGGAGACCATGAGTATTACTTGAAAGCTGCAGACAAAGCAGGGCGCACTGCGGTGGATGCTTTAGAAATCCAAGTCCGTAATCTGTTCCAAAAACAACCATCCCCTGTTAAATTTCATGCTAAGTTCCATGGGGATCACAATTCTGTGATTAACGATATTAATAAGAAAATTCTGCTAGTCAAAAAGCTGGCTTTTGCCTTTGGTGATAGAAACAGCAGCTCTATTACTTTGCATAATATCACCAAAGGTTCTGTGGTGGTGGACTGGACAAACAATACTTTCCCAACAGAACCATGTCCAGTAGAGCAAGTAGAAAGTGTTGGCAAAAAGATCTACGATGAACGTGGCAGTCCTCGTCAACATTTTGTTAACTCTGTGGAGCCAGAGTATAAACTTTTGAATATTTCTTTGTCTTTCACGGGAAGTTGTAAACATAAAAATTTCAGGTACATACCCATGAGACCAGAGGAACCCATTCCCACTGCGGTGGCACCGACTGTAGCTGCAGACAGAAACCCGGAGAAGAGCAGCGAAGATGATGTTTACCTTCACACTGTTATTCCTGCAGTGGTGGTGGCTGCCATTTTGTTAATTGCTGGCATCATAGCTATGATTTGTTATCGGAAGAAGAGGAAAGGCAAGTTGACCATAGAGGATCAGGCAACTTTTATCAAGAAGGGTGTTCCAATTATTTTTGCAGATGAGTTAGATGACTCCAAGCCTCCTCCTTCTTCCAGTATGCCACTGATTCTAAAGGAGGAGAAAGCTCCCCTTCCTCCTCCTGAGTATCCTAATCAAAATGTGCCAGAGACAATCCCTCTAAACCAAGACAGCTTGGGGGAGTACACACCTCTTAGGGATGAGGACCCCAATGCTCCCCCTTATCAACCTCCCCCACCTTTCACAACACCTATGGAAGGTAAAGGGTCACGCCCCAAAAACATGACCCCATACCGGTCACCACCCCCTTATGTACCTCCTTAATGAACGGTTTGCTGAGTGGGAGGAGAAAGGGGGCTGTGAGTTCCAAACCAGTGTTGTCTGAAGATTGATAGCCTGCAATCTGCTGTCAGGATAACAGGAAAACTCTGCTGTTCTAGGCAAAGAGTAAAGACCTGGAGACTTTTTATAGTAACTCCGCATTATACATGCCTCCTTCACAGATTGTGGAAAATATGGGACATATGTCATTTGCCTAACGATTTTTTTTTTCGTATTGGTATTCATACAGATGTGTGCTCCGTTCTAGATATTTAACAGATTGCAGGCTTTAAAGACACTAAAGAGGAAGTGATTGGACAATGTTGTTCAGCACTGGGGTGGCCTTTTGTTTCTCTGCTGTTTGCCTTTAACACTAACTGTATTATTATTATTTTTGGGGTTTTTTTTCCTTTTATTCACGTGTGTCTAGAGCTTCAGGTCATAATGAAGTGGTATGACGAAAGGTATCTTTGAAACGGAACATCATTACATTTACTCCTGTCTTCTATATATTTTAAGGACAGCTATCTATACTTAAAAAAAAATTCCAGCCGTGTTTCAAAAAGTTGTATTCCCAAGCATCGACTTTCCAGGTACCTGATTAGAAAACCATAGTGCGACACCGAGTTCCTGCTTAAAAACCTCCTTTCCCCTGGCATTTCTGTGCCCCGGGACCGGCCTTTAAACTTCATCGCCCTTGTCAAGATATGGCAAGCTTTCTGATCGAGAGCTCGTGCATGCAAAGCCTCTTTGGCTTTATTGAAACACAGCCATGTTTTTTTTTAGGTAAAGATAAAATACTTCACTTTGTTTTAATTCTGTTCCCCCACCACCAACAATGGTGTAGATACGGTGTGCAGTGGTCTGAATCAATGGCTTGCTACACCAACCCCATAGTCACAGCAAGTAATTACCCAACACATACTGGTGCTCTCCCCAAAACAGAAGGAAGCGAGCAATCACTTTTTTTTTAAAAAAAGATTTTTGATACAGCCTCAAATTGTTTTATTAAAAAGAAAACTTCTAAAATGGAAACGCTTCAAGCTATTTATATAACCTAAGGCATAACACGAGTGGTGATATCGCTTGCCTTTTCTGCTTTCCATAGGCCACTGTTGACATTTTAGAGCCATATTTTATGTTGTTTTTTTTTTTTTAAAAAAAAAAAAAAA
Protein		Refseq >NP_001016518\|dystroglycan 1 (dystrophin-associated glycoprotein 1) precursor [Xenopus (Silurana) tropicalis] MDIRCAALSLPMLRTIMVLLMASSAWSVWPSDPMEVVQDWDNQLEASMHSLFPEIKEAVAPMTGIPDSSAVVGRPFKIHIPTEFLASSGETIKIFEVGKEILPSWLHWEANFLQGLPLDGDKGVYDISVASMRLAPNGSYVTQTADVFAVEVHPEDHNEPQSVRVAGQETAEATPFLCGTDEPVTILTVILDADLTKMTPKQRVDLLNRMRDFSEVELYHMKLVPVVNNRLFDMSAFMAGPGNAKKVVENGALLSWKLGCGMDQNTVPNISSVEVPAKEGTMSAQLGYPVVGWHIANKKPQMPKRIRRQIYATPTPVTAIGPPTTAIHEPPERIVPTPTSPAIAPPTDTTAPPVREPIPLPGKPTVTIRTRGAIIHTPTLGPIHPTRIIETTSIVRPTITRHIFVEPTAAVTPPSTTTKRPRTTMKPPTPPTTDSSTTTTKKPTKKPRPRPPKPLATTKAPSTKVETTSPSRTRPSTSGVPNTDPELKNHIDKVVAWVGTYFEVKIPPDTFYDKEDGTTDNLQLSLAPRQKAGLGEKMWVMLNSTSQVMYGMPDYTHIGDHEYYLRAADKAGRTAVDALEIQVRNLFQKQPSTVKFHAKFHGDHNAVINDINKKILLVKKLAFAFGDRNSSSITLHNITKGSVVVDWTNNTFPVEPCPVEQVEGVGKKIYDERGSPRQHFVNAVEPEFKLLNISLSFSGSCKHKKFRYIPMRAEEPIPTAVAPTVAVDRNLEKRSEDDVYLHTVIPAVVVAAILLIAGIIAMICYRKKRKGKLTIEDQATFIKKGVPIIFADELDDSKPPPSSSMPLILKEEKAPLPPPEYPNQNVPETIPLNQDSLGEYTPLRDEDPNAPPYQPPPPFTAPMEGKGSRPKNMTPYRSPPPYVPP	Refseq >NP_001082480\|dystroglycan 1 (dystrophin-associated glycoprotein 1) precursor [Xenopus laevis] MDIRCAGLSLPMLRTIMVLLMASCAWSAWPSDPTEVAQDWDNQLEASMHSLFPEIKETVAPMTGIPDSSALVGRPFKIHIPTEFLASSGETIKISEVGKETLPSWLHWEGNFLQGLPLDGDKGVYDISVASLHLAPNGSYVPHTTDVFSVEVHPEDHNEPQSVRVAGQETAEAIPFLCGTDEPVTLLTVILDADLTKMTPKQRVDLLNRMRDFSEVELFHMKLVPVVNNRLFDMSAFMAGPGNAKKVVENGALLSWKLGCGMDQNTVPNISSVEVPAKEGTMSAQLGYPVVGWHIANKKPQMPKRIRRQIYATPTPVTAIGPPTTAIHEPPERIVPTPTSPAIAPPTDTTAPPVREPIPLPGKPTVTIRTRGAIIHTPTLGPIHPTRIIETTSIVRPTMTRPIYVEPTAAVTPPSTTTKRPRVTTMKPATPPTTDSSTTTTKKPTRKPRTRPPKPLATTKAPATKFETTSSSRTRTSTSGVPNTDPELKNHIDKVVAWVGTYFEVKIPPDTFYDREDGTTDNLQLTLVPRIKASAGEKMWVMLNSTSQVMYGMPDYIHIGDHEYYLKAADKAGRTAVDALEIQVRNLFQKQPSPVKFHAKFHGDHNSVINDINKKILLVKKLAFAFGDRNSSSITLHNITKGSVVVDWTNNTFPTEPCPVEQVESVGKKIYDERGSPRQHFVNSVEPEYKLLNISLSFTGSCKHKNFRYIPMRPEEPIPTAVAPTVAADRNPEKSSEDDVYLHTVIPAVVVAAILLIAGIIAMICYRKKRKGKLTIEDQATFIKKGVPIIFADELDDSKPPPSSSMPLILKEEKAPLPPPEYPNQNVPETIPLNQDSLGEYTPLRDEDPNAPPYQPPPPFTTPMEGKGSRPKNMTPYRSPPPYVPP

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.8621	Xl.16781 [+] Xl.34453
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		10 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	DAG1
mouse		MGI	Dag1	All(7) Targeted, knock Out(3) Targeted, other(3)
zebrafish		ZFIN	dag1	7 Lines(s)

Publications
First:		A role for the dystrophin-glycoprotein complex as a transmembrane linker between laminin and actin. [J Cell Biol 1993]
Most recent:		Dystroglycan is involved in skin morphogenesis downstream of the Notch signaling pathway. [Mol Biol Cell 2013]
		View All Papers 3 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		calcium ion binding protein binding
Biological:
Cellular Component:
EC:
KOG:		[W] Dystroglycan

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.8621.1.S1_at	Xl.13762.1.A1_at [+] Xl.17314.1.A1_at
Affymetrix 2.0			Xl2.16781.1.S2_at [+] Xl2.16781.1.S1_s_at Xl2.13762.2.S1_at Xl2.17314.2.S1_at Xl2.13762.1.A1_at Xl2.55795.1.S1_at Xl2.17314.1.A1_at

Symbol legend[+]