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Summary Expression Gene Literature (133) GO Terms (17) Nucleotides (402) Proteins (60) Interactants (1238) Wiki
XB-GENEPAGE-1018553
Gene Symbol:
fgfr1

Gene Name:
fibroblast growth factor receptor 1

Synonyms:
X1FGFR , XFGFR-1 , flt2 , flt-2 , xfgfr1 , cek , flg , ogd , flt2 , kal2 , bfgfr , fgfr-1 , fgfr1-a , fgfr1-b ( Add synonyms , Nomenclature history )

Gene Function:
receptor tyrosine kinase

Protein Function :
Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and ...[+]


InterPro :
SNARE , Syntaxin N , T SNARE dom , Syntaxin/epimorphin CS [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
hypogonadotropic hypogonadism 2 with or without anosmia [+]

OMIM:
JACKSON-WEISS SYNDROME; JWS [+]

External Links:
1/2
 
Xenbase Gene ID XB-GENE-1018554 XB-GENE-1018562 XB-GENE-6254218
Gene Symbol fgfr1 fgfr1.L fgfr1.S
Chromosome Chr03 chr3L chr3S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 548648
399444
394418
mRNA RefSeq RefSeq RefSeq
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine fgfr1 fgfr1.L fgfr1.S
Phenotype X. tropicalis X. laevis.L X. laevis.S
Smith Morpholino Screen tneu076b03      
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards FGFR1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Fgfr1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Fgfr1 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR fgfr1b fgfr1a ZFIN Ensembl
chicken
GEISHA FGFR1 Ensembl
fruit fly
worm
Publications
First Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in Xenopus embryos., Cell 1991  
Most Recent A comparative analysis of fibroblast growth factor receptor signalling during Xenopus development., Biol Cell 2020                  
All View All Papers 20 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 4 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 13 terms 4 terms 8 terms
PANTHER fgfr1
KEGG Pathways K04362 K04362 K04362
KOG [T] Fibroblast/platelet-derived growth factor receptor and related receptor tyrosine kinases
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks fgfr1
Antibodies Fgfr1 Ab2 Fgfr1 Ab2 Fgfr1 Ab2
Morpholinos fgfr1 MO1 , fgfr1 MO2 , fgfr1 MO3 , fgfr1 MO4 fgfr1 MO1 , fgfr1 MO2 , fgfr1 MO3 , fgfr1 MO4 fgfr1 MO1 , fgfr1 MO2 , fgfr1 MO3 , fgfr1 MO4
ORFs fgfr1 ORF1 fgfr1.L ORF1
Clones EXRC Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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