tcf7l1 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (42)

Nucleotides (293)

Interactants (134)

XB-GENEPAGE-1031984

Gene Symbol: tcf7l1 Gene Name: transcription factor 7-like 1 (T-cell specific, HMG-box) Synonyms: tcf3c, tcf3d, XTCF-3, xtcf3 Add Xenopus synonyms Gene Function: high mobility group transcription factor Interactants: tcf3(38) , sia1(17) , lef1(15) , nodal3.1(12) , wnt8a(10) , tcf4(9) , chrd(8) View All

XB-GENE-1031985

XB-GENE-6252329

XB-GENE-1031992

Molecules		tropicalis	laevis a		laevis b
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene		Entrez Gene
mRNA		Refseq >NM_001005640\|Xenopus (Silurana) tropicalis transcription factor 7-like 1 (T-cell specific, HMG-box) (tcf7l1), mRNA GGGGGAGCCTGCATGTGCACTCTAGGGGGGTGGGAGACACAACTTTCAGGGGGTCTAGCCGGAAAGTGCAGCTGAATCCATTCCTTCTGTGCGGGAAGTTGGGAGAGAAGTTTTTTTGGGGGGTGTCTCTCACCTGGATGGAGGATTTGGCGAGCCCTCTGTAAAGGAGAAGTAGTCCGCGACTTTCACAAGGGACTGTCTGAGCGGAGGGTTGTCGGTGGGTACCGCCGGCGGAGGAGTCGCACCATGCCTCAGCTAAACAGCGGCGGGGGGGACGAACTAGGGGCTAACGACGAGCTCATCCGATTTAAAGACGAAGGGGAGCAAGAAGAGAAGAGCCCCGGGGAGGGCTCCGCGGAAGGGGATTTGGCCGACGTGAAATCCTCGCTGGTCAATGAGTCGGAGAATCACAGCAGCGATTCGGACTCGGAGGTCGAAAGGCGCCCTCCTCCAAGGGAAACCTTTGAGAAGCCTCGGGATTATCTATCTGAAGCATTTCGGAGGCAACAGGATGCAGCATTCTTCAAGGGACCCCCTTATGCCGGGTATCCTTTCCTGATGATTCCAGATCTTGGAGGGCATTACTTGCCCAATGGTGCCCTCTCACCCAGTGCCCGCACGTACTTACAGATGAAATGGCCCCTACTGGATTCCCCCAGTACGGCTGGTTTAAAAGATGCCCGGTCGCCATCCCCTGCCCACCTGTCCAACAAGGTTCCGGTGGTACAGCACCCACACCACATGCACCCACTGACACCTCTCATCACCTACAGCAATGAACACTTCTCTCCGGGAACCCCTCCTGGGCACCTCTCTCCAGAGATAGACCCAAAGACTGGGATCCCTCGCCCACCTCACCCATCAGAGCTATCTCCATATTATCCACTTTCTCCAGGGGCAGTGGGACAGATTCCTCACCCGCTTGGCTGGCTAGTACCTCAGCAGGGCCAGCCAATGTACTCCATCCCTCCTGGCGGATTCAGGCACCCATATCCTGCACTGGCAATGAACGCCTCTATGTCCAGTTTGGTGTCCAGCCGGTTTTCGCCTCACATGGTGCCACCGCCACATCATGGCCTTCATACCTCGGGGATCCCGCACCCTGCCATTGTTTCACCCATCGTGAAACAGGAGCCATCCTCTGGGAACATCAGTCCTAACCTCATCACGAAGCCCAGTGTAGTAGTAAAGAAGGAAGAAGAGAAGAAGCCTCATATTAAAAAGCCACTGAATGCCTTTATGCTGTACATGAAAGAGATGAGAGCTAAGGTGGTGGCAGAGTGTACCCTGAAAGAGAGCGCAGCTATCAACCAGATTCTAGGACGTAGGTGGCATTCATTGTCTCGGGAAGAGCAGGCCAAGTACTATGAGCTGGCACGGAAAGAGAGGCAACTTCATTCTCAGCTGTACCCCACCTGGTCTGCACGTGACAACTATGGCAAAAGAAAGAAACGGAAGAGAGATAAGCAGTCACCTGAAATGGAAATTACAAAGACAAAGAAGATGTGTGTTCAGCACCTTCCAGCAGATAAGTCCTGTGACAGTCCCGCTTCTTCACATGGCAGCATGCTGGACTCACCAGCCACTCCGTCTGCTGCTCTGGCTTCTCCTGCAGCACCCGCTGCCACCCATTCAGAGCAAGCTCAGCCACTCTCCCTCACCACCAAGCCTGAAGCTAGAGCGCAGCTCTCTCTCAGCCACTCTGCTGCTTTCCTGGCTTCCAAATCGCCTCCATCCTCAAGTCTTTCAGGATCCCTGTCTTCCCCAGTTGGCTCTCCGCTGCTGTCCAGACCAATCCCACTGACATCTTCCATTCTGTCCCCACCGTGCGTCTTCCCCTCTGCACTGCAAGCACTACCACTGCTGCAGGCACAGCCCCTCTCTCTGGTGACCAAATCCAGTGACTGATGAAAGAGAGACTATATACCTGGACAACCAGGACTTGATCACCCAAAAGCACTAGTGCTGTGTGGATCTGGATGTACAATGCTCTGCACTAGTGTATCAATTGTCTGCAGATATGGACTGCTGTCTGCATTGGTGTATATGATGTCCTGAGTATATGGACTGTTACACTGCTTTTCATTCTCCGGTATAATGTAGCTATGGACACAGCTCTGCACTGGTGCATATATATATATATATATTTACTTTTGGCATTGTGTGTAACCCTCTGCAGATGCACATGTGGGAAGCTCATCCGTGCACAGGAGAACAGTCCTCCTTTTTTTTTTCTTTTTATATGATGGACCTTGAACCTCTCCATGTTTGCTGCACAAAAGGGCACGTGCATCAATGGCGGCAGCAGCACCCATGGATCCAATTCCAGCATAGGCAATGCATTGTGTTATTGCAGGCTCATTGCTGAGGCACCCAGGCTATACCTCCTCTCCAGCATTCAGCAGCTTCAACAAAGATGGCAGCTGCCAACAGACCTGCAAGAATTATTGGTCAATATTTGACCTGCTGGCTCCAGCTCTGCAGATCACACCCGTCCATCTTCTACTTTTCTCATTATTATCCGGGAAAGACACTTTTATTTTTCATCAGTCGGGAAGAAAACTTAACTATTAATTTTAGTCAGTCACAACAGCGGAAAGTGTAAATTGTACATAAGAGTGCGTCCGAGGGGTTGGTGCATGTTTATTTTGTTAGGTTAATCTTTATATGTTACTTTTTTTTTTAATTCTTTAATAAAGGGGCAAAAGCAAGTTCTTGCCTGCAAGTGCTGGTCCGGATGCCAGAGCCAAATTTTCAACGCTGCTTTTGGCATTGCCCAGGTTACTATTTTCCTCCCCCTTCACTTGTTCTGTTCCATTCCAGTCCTCTCTTTCAAGTTTATTTTATTTTTTTAATGGAAAAAAAGGAAAAAAAAAATCTTGAAAATGTGACCTTTTTTTGTAACAAAATAGAAAATATATTGTGTTTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001088014\|Xenopus laevis transcription factor 7-like 1 (T-cell specific, HMG-box) (tcf7l1-a), mRNA GGGACTGTGTGAGCGGAGTGTTGTCGGTAGCGCCGGCGGAGGAGTCTCATCATGCCTCAACTAAACAGCGGCGGGGGGGACGAGCTCGGGGCTAACGACGAACTCATCCGATTTAAAGACGAGGGGGAGCAAGAAGAGAAGAGCCCCGGGGAGGGATCCGCCGAGGGGGATCTGGCCGACGTCAAATCCTCGCTGGTTAATGAGTCGGAGAATCACAGCAGCGATTCGGACTCGGAGGTCGAGAGGCGCCCCCCTCCAAGGGAAGCCTTTGAGAAGCATAGGGATTATCTAACTGAAGCACTTCGGAGGCAACAGGATGCAGCGTTCTTCAAGGGACCCCCTTATGCTGGGTATCCTTTCCTGATGATCCCAGATCTTGGAGGGCATTACTTGCCCAACGGTGCCCTTTCACCCAGCGCCCGAACGTACTTACAGATGAAATGGCCCCTACTGGATTCCCCTAGTACGGCTGGTTTAAAAGATGCCCGGTCGCCATCCCCTGCCCACTTGTCCAACAAGGTTCCTGTGGTACAGCACCCACACCACATGCACCCACTTACGCCTCTCATCACCTATAGCAACGAACACTTCTCTCCAGGAACCCCTCCTGGGCACCTCTCTCCAGAGATAGACCCCAAGACTGGGATCCCTCGTCCACCTCACCCATCAGAGTTATCTCCATATTACCCATTATCTCCAGGGGCAGTGGGACAGATTCCTCACCCGCTTGGCTGGCTAGTGCCTCCGCAGGGTCAGCCAATGTATTCCATCCCTCCTGGCGGATTTAGGCACCCATATCCTGCACTGGCAATGAATGCATCTATGTCCAGTTTGGTGTCCAGCCGTTTTTCACCTCACATGGTGCCACCGCCGCATCACAGCCTTCATACCTCGGGAATCCCACACCCTGCCATTGTTTCGCCCATTGTGAAACAGGAGCCGTCCTCTGGGAACATTAGTCCCAACCTACACACGAAGTCCAATATGATAGTAAAGAAGGAAGAAGAGAAGAAGCCCCACATTAAGAAGCCACTGAATGCCTTCATGCTGTACATGAAAGAGATGAGGGCTAAGGTAGTGGCAGAGTGTACGCTGAAAGAGAGTGCAGCTATCAACCAGATTCTAGGCCGCCGGTGGCATTCCTTGTCTCGGGAAGAGCAGGCCAAGTACTATGAGCTGGCACGAAAGGAGAGGCAACTTCATTCTCAGCTGTACCCCTCTTGGTCTGCACGTGACAACTATGGCAAAAGAAAGAAACGGAAGAGAGAAAAGCAGTCACCTGAGATGGAAACCCACACCAAGACAAAGAAGATGTGTGTTCAACACCTTCCAGCTGATAAATCCTGTGACAGTCCCGCCTCATCCCATGGCAGCATGCTGGACTCACCAGCCACTCCGTCTGCTGCTCTGGCTTCTCCTGCAGCACCCGCTGCCACTCACTCTGAGCAAGCTCAGCCGCTCTCCCTCACCACCAAGCCTGAAGCTAGAGCACAGCTTTCTCTCAGTCACTCTGCTGCTTTCCTGGCTTCTAAATCTCCTTCGTCCTCAAGTTTTTCAGGACACCTGTCTTCCCCTGTTGGCTCTCCACTTCTCTCCAGGCCAATCCCACTGACCTCTTCCATTTTGTCCCCATCGGGTGTCTTCCCATCCGCACTGCAAGCACTACCACTGCTGCAGGCACAGCCCCTTTCTCTGGTGACCAAATCCAGTGACTGATGATGGAGAATCCTATATACTTGGACAACCGGGGATCGATCAACTAAAAGCACTAGTGCTGTGTGGATCTGGATGTACAATGCGCTGCACTAGTGTATCAACTGTCTGCAGATATGGACTGCTATCTGCAGTGGTGTATATGATGTAACGATATGAACTGTTACACTGCTTTCATTGTCA		Refseq >NM_001087469\|Xenopus laevis transcription factor 7-like 1 (T-cell specific, HMG-box) (tcf7l1-b), mRNA GTCTCATCATGCCTCAGCTCAACAGCGGCGGCGGGGACGAGCTCGGGGCTAACGACGAGCTCATCCGATTTAAAGACGAAGGGGAGCAAGAAGAAAAGAGTCCCGGGGAGGGCTCCGCGGAGGGGGATCTGGCCGACGTGAAATCCTCGCTGGTCAATGAGTCGGAGAATCACAGCAGCGATTCGGATTCAGAGGTGGAGAGGCGTCCCCCTCCGAGGGAAACCTTTGAGAAGCCTAGGGATTATCTATCTGAAGCGTTTCGGAGGCAACAGGATGCAGCGTTCTTCAAGGGACCTCCTTATGCTGGGTATCCTTTCCTGATGATCCCAGATCTTGGAGGGCATTACTTGCCCAATGGTGCCCTCTCACCCAGCGCTCGCGCGTACTTACAGATGAAATGGCCCCTATTGGATTCCCCCAGTACGGCTGGTTTAAAAGATGCCCGCTCGCCATCCCCTGCCCACCTGTCCAACAAGGTTCCAGTGGTACAGCACCCACACCACATGCACCCATTGACTCCTCTCATCACCTACAGCAACGAACACTTCTCTCCTGGAACCCCTCCTGGCCACCTCTCTCCAGAAATAGACCCCAAGACTGGGATCCCTCGCCCACCTCACCCATCAGAGTTATCTCCATATTATCCATTATCTCCAGGGGCAGTGGGACAGATTCCTCACCCGCTTGGCTGGCTCGTTCCTCAGCAGGGCCAACCAATGTACTCCATCCCTCCTGGAGGATTTCGGCACCCATATCCTGCACTGGCAATGAACGCATCTATGTCCAGTTTGGTGTCCAGCCGTTTTTCACCTCACATGGTGCCACCTCCACATCACAGCCTTCATACCTCTGGGATCCCACACCCTGCCATTGTCTCGCCCATTGTGAAACAGGAGCCGTCCTCTGGGAACATCAGTCCTAACCTCAGCACGAAGTCCAATGTGGTAGTAAAGAAGGAAGAAGAGAAGAAGCCCCACATTAAGAAGCCACTGAATGCCTTCATGCTGTACATGAAAGAGATGAGAGCTAAGGTGGTGGCAGAGTGTACTCTGAAAGAGAGCGCAGCTATTAACCAGATTCTAGGCCGTAGGTGGCATTCCTTGTCTCGGGAAGAACAGGCCAAGTACTATGAGCTGGCACGGAAGGAGAGGCAACTTCATTCTCAGCTGTACCCCTCTTGGTCTGCACGTGACAACTATGGCAAGAAGAAGAAACGGAAGAGAGAAAAGCAGTCGCCTGAGATGGAAAACTACACCAAGACAAAGAAGATGTGTGTTCAGCATTTTCCATCTGATAAGTCCTGTGACAGTCCCGCTTCTTCCCATGGCAGCATGCTCGACTCGCCAGCTACTCCGTCTGCTGCTCTGGCTTCTCCTGCAGCACCCGCTGCCACCCACTCCGAGCAAGCTCAGCCACTCTCCCTCACCACCAAGCCTGAAGCTAGAGCACTCAGCCACTCTGCTGCTTTCCTAGCTTCTAAATCACCTTCATCCTCCAGTCTTTCAGGACACCTGCCTTCCCCTGTTGGCTCTCCGCTGCTCTCCAGACCAATCCCACTGACATCTTCCATTTTGTCCCCACCGGGTGTCTTCCCTTCTGCACTGCAAGCACTACCACTGCTGCAGGCACAGCCCCTTTCTCTAGTGACCAGATCCAGTGACTGATGAGAGAGACTCCTATATACCTGGACAACCATCACCTAAAAGCACTAGTGCTGTGTGGATCTGGATGTACAATGCTCTGCACTAGTCTATCAATTGTCTGCAGATTTGAACTGCTGTCTACAATGGTGTATATGATGTCCTACGTATATGGACTGTAACACTGCTTTTNGTTGTCATGTATAATAT
Protein		Refseq >NP_001005640\|transcription factor 7-like 1 [Xenopus (Silurana) tropicalis] MPQLNSGGGDELGANDELIRFKDEGEQEEKSPGEGSAEGDLADVKSSLVNESENHSSDSDSEVERRPPPRETFEKPRDYLSEAFRRQQDAAFFKGPPYAGYPFLMIPDLGGHYLPNGALSPSARTYLQMKWPLLDSPSTAGLKDARSPSPAHLSNKVPVVQHPHHMHPLTPLITYSNEHFSPGTPPGHLSPEIDPKTGIPRPPHPSELSPYYPLSPGAVGQIPHPLGWLVPQQGQPMYSIPPGGFRHPYPALAMNASMSSLVSSRFSPHMVPPPHHGLHTSGIPHPAIVSPIVKQEPSSGNISPNLITKPSVVVKKEEEKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHSLSREEQAKYYELARKERQLHSQLYPTWSARDNYGKRKKRKRDKQSPEMEITKTKKMCVQHLPADKSCDSPASSHGSMLDSPATPSAALASPAAPAATHSEQAQPLSLTTKPEARAQLSLSHSAAFLASKSPPSSSLSGSLSSPVGSPLLSRPIPLTSSILSPPCVFPSALQALPLLQAQPLSLVTKSSD UniProtKB	Refseq >NP_001081483\|transcription factor 7-like 1-A [Xenopus laevis] MPQLNSGGGDELGANDELIRFKDEGEQEEKSPGEGSAEGDLADVKSSLVNESENHSSDSDSEVERRPPPREAFEKHRDYLTEALRRQQDAAFFKGPPYAGYPFLMIPDLGGHYLPNGALSPSARTYLQMKWPLLDSPSTAGLKDARSPSPAHLSNKVPVVQHPHHMHPLTPLITYSNEHFSPGTPPGHLSPEIDPKTGIPRPPHPSELSPYYPLSPGAVGQIPHPLGWLVPPQGQPMYSIPPGGFRHPYPALAMNASMSSLVSSRFSPHMVPPPHHSLHTSGIPHPAIVSPIVKQEPSSGNISPNLHTKSNMIVKKEEEKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHSLSREEQAKYYELARKERQLHSQLYPSWSARDNYGKRKKRKREKQSPEMETHTKTKKMCVQHLPADKSCDSPASSHGSMLDSPATPSAALASPAAPAATHSEQAQPLSLTTKPEARAQLSLSHSAAFLASKSPSSSSFSGHLSSPVGSPLLSRPIPLTSSILSPSGVFPSALQALPLLQAQPLSLVTKSSD UniProtKB		Refseq >NP_001080938\|transcription factor 7-like 1-B [Xenopus laevis] MPQLNSGGGDELGANDELIRFKDEGEQEEKSPGEGSAEGDLADVKSSLVNESENHSSDSDSEVERRPPPRETFEKPRDYLSEAFRRQQDAAFFKGPPYAGYPFLMIPDLGGHYLPNGALSPSARAYLQMKWPLLDSPSTAGLKDARSPSPAHLSNKVPVVQHPHHMHPLTPLITYSNEHFSPGTPPGHLSPEIDPKTGIPRPPHPSELSPYYPLSPGAVGQIPHPLGWLVPQQGQPMYSIPPGGFRHPYPALAMNASMSSLVSSRFSPHMVPPPHHSLHTSGIPHPAIVSPIVKQEPSSGNISPNLSTKSNVVVKKEEEKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHSLSREEQAKYYELARKERQLHSQLYPSWSARDNYGKKKKRKREKQSPEMENYTKTKKMCVQHFPSDKSCDSPASSHGSMLDSPATPSAALASPAAPAATHSEQAQPLSLTTKPEARALSHSAAFLASKSPSSSSLSGHLPSPVGSPLLSRPIPLTSSILSPPGVFPSALQALPLLQAQPLSLVTRSSD UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis a		laevis b
UniGene		Str.11534 [+] Str.56596	Xl.1100		Xl.85456 [+] Xl.69404 Xl.75401
Unigene EST Profile		EST Profile	EST Profile		EST Profile
GEO data			GEO		GEO
Images		4 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	TCF7L1
mouse		MGI	Tcf7l1	All(5) Targeted, knock Out(1) Targeted, other(3)
zebrafish		ZFIN ZFIN	tcf7l1b tcf7l1a	1 Lines(s) 9 Lines(s)

Publications
First:		XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos. [Cell 1996]
Most recent:		Subfunctionalization and neofunctionalization of vertebrate Lef/Tcf transcription factors. [Dev Biol 2012]
		View All Papers 6 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		DNA binding
Biological:		regulation of transcription, DNA-dependent
Cellular Component:
EC:
KOG:		[K] Transcription factor TCF-4

Reagents		tropicalis	laevis a		laevis b
Clones		open biosystems	open biosystems		open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes		geneservice/RZPD imagenes
Affymetrix 1.0		Str.24440.1.S2_at [+] Str.24440.1.S1_at Str.11534.1.A1_at Str.11534.1.A1_s_at			Xl.46.1.S1_at [+] Xl.1100.1.S1_at Xl.2993.1.A1_at
Affymetrix 2.0					Xl2.46.2.S1_a_at [+] Xl2.1100.1.S1_at Xl2.2993.2.A1_at Xl2.2993.1.S1_at

Symbol legend[+]