Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (250) GO Terms (21) Nucleotides (196) Proteins (48) Interactants (712) Wiki
XB-GENEPAGE-1194371
Gene Symbol:
foxh1

Gene Name:
forkhead box H1

Synonyms:
fast1 , fast-1 , XFast-1 , xfoxh1 , xfast1 , foxh1a ( Add synonyms , Nomenclature history )

Gene Function:
winged helix transcription factor

Protein Function :
Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Upon TGF-beta induction, forms a transcriptionally active complex with smad2 and smad4 called activin-responsiv...[+]


InterPro :
Cyt P450 , Cyt P450 E grp-I , Cyt P450 CS , Cyt P450 sf [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
holoprosencephaly 1

OMIM:
HOLOPROSENCEPHALY 1; HPE1

External Links:
GEO Series :
GSE53653.
 
Xenbase Gene ID XB-GENE-1194372 XB-GENE-1194377 XB-GENE-17346750
Gene Symbol foxh1 foxh1.L foxh1.S
Chromosome Chr6 chr6L chr6S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 549838
398070
108719776
mRNA RefSeq NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine foxh1 foxh1.L foxh1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards FOXH1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Foxh1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Foxh1 Ensembl
zebrafish
ZFIN, AGR foxh1 ZFIN Ensembl
chicken
fruit fly
worm
Publications
First A transcriptional partner for MAD proteins in TGF-beta signalling., Nature 1996  
Most Recent Generation of a FOXH1 homozygous knockout human embryonic stem cell line by CRISPR/Cas9 system., Stem Cell Res 2020    
All View All Papers 8 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 15 terms 16 terms 0 term
PANTHER foxh1
KEGG Pathways K09400 K09400
KOG [K] Transcription factor of the Forkhead/HNF3 family
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks foxh1
Antibodies Foxh1 Ab1 Foxh1 Ab1
Morpholinos foxh1 MO1 , foxh1 MO2 foxh1 MO1 , foxh1 MO2 foxh1 MO1 , foxh1 MO2
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list