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Summary Expression Gene Literature (138) GO Terms (35) Nucleotides (378) Proteins (44) Interactants (657) Wiki
XB-GENEPAGE-941539
Gene Symbol:
plk1

Gene Name:
polo like kinase 1

Synonyms:
PLK-1 , Plx1 , plk , polo-like kinase 1 ( Add synonyms , Nomenclature history )

Gene Function:
serine/threonine kinase

Protein Function :
Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of co...[+]



Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-941540 XB-GENE-17331487 XB-GENE-941545
Gene Symbol plk1 plk1.L plk1.S
Chromosome Chr9 chr9_10L chr9_10S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 407937
108701628
380481
mRNA RefSeq NCBI Nucleotide RefSeq
Protein RefSeq Swiss-Prot  More.. NCBI Protein RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine plk1 plk1.L plk1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards PLK1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Plk1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Plk1 Ensembl
zebrafish
ZFIN, AGR plk1 ZFIN Ensembl
chicken
GEISHA PLK1 Ensembl
fruit fly
worm
Publications
First Purification and molecular cloning of Plx1, a Cdc25-regulatory kinase from Xenopus egg extracts., Science 1996  
Most Recent Polo-like kinase 1 (Plk1) is a positive regulator of DNA replication in the Xenopus in vitro system., Cell Cycle 2020  
All View All Papers 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 21 terms 6 terms 23 terms
PANTHER plk1
KEGG Pathways K06631 K06631 K06631
KOG [D] Polo-like serine/threonine protein kinase
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks plk1
ORFs plk1 ORF1 plk1.S ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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