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Summary Expression Gene Literature (13) GO Terms (18) Nucleotides (204) Proteins (59) Interactants (213) Wiki
XB-GENEPAGE-480066
Gene Symbol:
tnik

Gene Name:
TRAF2 and NCK interacting kinase

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
germinal center kinase

Protein Function :



Interactants:
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Diseases: 


Disease Ontology:
autosomal recessive non-syndromic intellectual disability

OMIM:
MENTAL RETARDATION, AUTOSOMAL RECESSIVE 54; MRT54

External Links:
 
Xenbase Gene ID XB-GENE-480067 XB-GENE-17340748 XB-GENE-865338
Gene Symbol tnik tnik.L tnik.S
Chromosome Chr5 chr5S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2
CDS Gene model Gene model
Entrez Gene 100493253
443633
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine tnik tnik.L tnik.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards TNIK OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Tnik MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Tnik Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR tnika tnikb ZFIN Ensembl
chicken
GEISHA TNIK Ensembl
fruit fly
worm
Publications
First Traf2- and Nck-interacting kinase is essential for canonical Wnt signaling in Xenopus axis formation., J Biol Chem 2010  
Most Recent Role of the Rap2/TNIK kinase pathway in regulation of LRP6 stability for Wnt signaling., Biochem Biophys Res Commun 2013          
All View All Papers 2 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 17 terms 0 term 3 terms
PANTHER tnik
KEGG Pathways K08840
KOG [T] Traf2- and Nck-interacting kinase and related germinal center kinase (GCK) family protein kinases
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks tnik
Morpholinos tnik MO1 , tnik MO2 , tnik MO3 tnik MO1 , tnik MO2 , tnik MO3 tnik MO1 , tnik MO2 , tnik MO3
ORFs tnik.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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