|
XB-GENEPAGE-478083
Gene Symbol:
tbx1
Gene Name: T-box 1
Synonyms:
xtbx1
,
cafs
,
cthm
,
dgcr
,
dorv
,
vcfs
,
tbx1c
,
tbx1-b
,
tbx1-a
( Gene Function: T-box transcription factor Protein Function
![]()
Transcriptional activator involved in head and pharyngeal arch development. Induces pre-placodal ectoderm (PPE) gene expression in regions where RIPPLY3 is absent. Plays a role in the formation of the ...[+]
Interactants:
Loading ...
Diseases: Disease Ontology:
DiGeorge syndrome
OMIM:
CONOTRUNCAL HEART MALFORMATIONS; CTHM
External Links:
|
|
Xenbase Gene ID | XB-GENE-478084 | XB-GENE-478088 | XB-GENE-6254396 | |||||
Gene Symbol | tbx1 | tbx1.L | tbx1.S | Chromosome | Chr1 | chr1L | chr1S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
![]() |
Version 9.1
![]() |
Version 9.1
![]() |
|||||
CDS |
Gene model
![]() |
Gene model
![]() |
Gene model
![]() |
|||||
Entrez Gene |
619587
|
735223
|
399188
|
|||||
mRNA |
RefSeq
![]() ![]() |
NCBI Nucleotide
![]() ![]() |
NCBI Nucleotide
![]() ![]() |
|||||
Protein
![]() |
![]() ![]() ![]() ![]() |
![]() ![]() ![]() ![]() |
![]() ![]() ![]() ![]() |
|||||
Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser) |
||||||||
Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
|
|||||||
More Information |
|
|||||||
Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | tbx1 | tbx1.L | tbx1.S | |||||
Orthology |
|
|||||||
human |
|
|||||||
mouse |
|
|||||||
rat |
|
|||||||
zebrafish |
|
|||||||
chicken |
|
|||||||
fruit fly |
|
|||||||
worm |
|
|||||||
Publications | ||||||||
First |
Isolation and characterization of a gene from the DiGeorge chromosomal region homologous to the mouse Tbx1 gene., Genomics 1997 |
|||||||
Most Recent |
Novel truncating mutations in CTNND1 cause a dominant craniofacial and cardiac syndrome., Hum Mol Genet 2020 ![]() |
|||||||
All | View All Papers 8 paper(s) referencing morpholinos 4 paper(s) referencing OMIMs 6 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 23 terms | 9 terms | 8 terms | |||||
PANTHER | tbx1 | |||||||
KEGG Pathways | K10175 | K10175 | K10175 | |||||
KOG |
[K] TBX1 and related T-box transcription factors
|
|||||||
Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | tbx1 | |||||||
Morpholinos | tbx1 MO1 , tbx1 MO2 , tbx1 MO3 , tbx1 MO4 | tbx1 MO1 , tbx1 MO2 , tbx1 MO3 , tbx1 MO4 | tbx1 MO1 , tbx1 MO2 , tbx1 MO3 , tbx1 MO4 | |||||
ORFs | tbx1.L ORF1 | |||||||
Clones | Horizon Source BioScience | EXRC Horizon Source BioScience | Horizon Source BioScience | |||||
Plasmids | Addgene | Addgene |
Symbol legend:



