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Summary Expression Gene Literature (40) GO Terms (22) Nucleotides (115) Proteins (33) Interactants (760) Wiki
XB-GENEPAGE-478083
Gene Symbol: tbx1

Gene Name: T-box 1

Synonyms: xtbx1 , cafs , cthm , dgcr , dorv , vcfs , tbx1c , tbx1-b , tbx1-a ( Add synonyms , Nomenclature history )

Gene Function: T-box transcription factor

Protein Function :
Transcriptional activator involved in head and pharyngeal arch development. Induces pre-placodal ectoderm (PPE) gene expression in regions where RIPPLY3 is absent. Plays a role in the formation of the ...[+]


Interactants: Loading ...
Disease Ontology: DiGeorge syndrome [+]

OMIM Diseases: CONOTRUNCAL HEART MALFORMATIONS; CTHM [+]

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Xenbase Gene ID XB-GENE-478084 XB-GENE-478088 XB-GENE-6254396
Gene Symbol tbx1 tbx1.L tbx1.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.1 Version 9.1
CDS Gene model
Entrez Gene: 619587
Entrez Gene: 735223
Entrez Gene: 399188
mRNA RefSeq RefSeq RefSeq
Protein RefSeq Swiss-Prot TrEMBL RefSeq Swiss-Prot TrEMBL RefSeq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine tbx1 tbx1.L tbx1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards TBX1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Tbx1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR tbx1 ZFIN Ensembl
chicken
GEISHA TBX1 Ensembl
fruit fly
worm
WORMBASE
Publications
First Isolation and characterization of a gene from the DiGeorge chromosomal region homologous to the mouse Tbx1 gene., Genomics 1997  
Most Recent The Wnt inhibitor Dkk1 is required for maintaining the normal cardiac differentiation program in Xenopus laevis., Dev Biol 2019                                    
All View All Papers 8 paper(s) referencing morpholinos 3 paper(s) referencing OMIMs 4 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 21 terms 9 terms 8 terms
PANTHER tbx1
KEGG Pathways K10175 K10175 K10175
KOG [K] TBX1 and related T-box transcription factors
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones   EXRC - 1 clone(s)  
Horizon Horizon Horizon
Morpholino tbx1 MO1 , tbx1 MO2 , tbx1 MO3 , tbx1 MO4 tbx1 MO1 , tbx1 MO2 , tbx1 MO3 , tbx1 MO4 tbx1 MO1 , tbx1 MO2 , tbx1 MO3 , tbx1 MO4
ORF tbx1.L ORF1
Affymetrix 1.0 Str.49461.1.S1_at [+] Xl.13224.1.A1_at Xl.21661.1.S1_at
Affymetrix 2.0 Xl2.51448.1.S1_at Xl2.21661.1.S1_s_at [+]

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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