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Summary Expression Gene Literature (34) GO Terms (9) Nucleotides (112) Proteins (30) Interactants (296) Wiki
XB-GENEPAGE- 478083

Gene Symbol: tbx1

Gene Name: T-box 1

Synonyms: xtbx1 , cafs , cthm , dgcr , dorv , vcfs , tbx1c , tbx1-b , tbx1-a
Add Xenopus synonyms , Nomenclature history


Gene Function: T-box transcription factor

Protein Function:
Transcriptional activator involved in head and pharyngeal arch development. Induces pre-placodal ectoderm (PPE) gene expression in regions where RIPPLY3 is absent. Plays a role in the formation of the ...[+]


Interactants: YYY

OMIM Disease Associations: CONOTRUNCAL HEART MALFORMATIONS; CTHM TRUNCUS ARTERIOSUS COM... [+]
1/3
 
Xenbase Gene ID XB-GENE-478084 XB-GENE-478088 XB-GENE-6254396
Gene Symbol tbx1 tbx1.L tbx1.S
Chromosome scaffold_1 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq Swiss-Prot TrEMBL Refseq Swiss-Prot TrEMBL Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v7.1 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.49461 Xl.85545 [+] Xl.51448 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 21 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine tbx1 tbx1.L tbx1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards TBX1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Tbx1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN tbx1 ZFIN Ensembl
chicken
GEISHA TBX1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Isolation and characterization of a gene from the DiGeorge chromosomal region homologous to the mouse Tbx1 gene. [Genomics 1997]
Most recent: Conservatism and variability of gene expression profiles among homeologous transcription factors in Xenopus laevis. [Dev Biol 2017]
View All Papers 8 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 9 terms 9 terms 9 terms
EC
PANTHER tbx1
KEGG Pathways K10175 K10175 K10175
KOG [K] TBX1 and related T-box transcription factors
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones   EXRC - 1 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Morpholino tbx1 MO1 , tbx1 MO2 , tbx1 MO3 , tbx1 MO4 tbx1 MO1 , tbx1 MO2 , tbx1 MO3 , tbx1 MO4 tbx1 MO1 , tbx1 MO2 , tbx1 MO3 , tbx1 MO4
ORF tbx1 ORF1
Affymetrix 1.0 Str.49461.1.S1_at [+] Xl.13224.1.A1_at Xl.21661.1.S1_at
Affymetrix 2.0 Xl2.51448.1.S1_at Xl2.21661.1.S1_s_at [+]

Symbol legend[+]

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