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Summary Expression Gene Literature (51) GO Terms (23) Nucleotides (382) Proteins (48) Interactants (992) Wiki
XB-GENEPAGE-478451
Gene Symbol:
crx

Gene Name:
cone-rod homeobox

Synonyms:
otx5 , Xotx5 , Xotx5b , otx5b , crx-a , crx-b ( Add synonyms , Nomenclature history )

Gene Function:
homeodomain transcription factor

Protein Function :
Transcription factor involved in anterior and eye development. Promotes the differentiation of both rod and cone photoreceptors cells in the retina. Together with other retinal homeobox proteins, acts ...[+]



Interactants:
Loading ...

Diseases: 


Disease Ontology:
cone-rod dystrophy 2 [+]

OMIM:
CONE-ROD DYSTROPHY 2; CORD2 [+]

External Links:
1/5
 
Xenbase Gene ID XB-GENE-478452 XB-GENE-865179 XB-GENE-6252876
Gene Symbol crx crx.L crx.S
Chromosome Chr08 chr8L chr8S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 548775
398118
373653
mRNA RefSeq RefSeq RefSeq
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine crx crx.L crx.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards CRX OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Crx MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Crx Ensembl
zebrafish
ZFIN, AGR crx ZFIN Ensembl
chicken
GEISHA OTX5 Ensembl
fruit fly
worm
Publications
First Gene expression screening in Xenopus identifies molecular pathways, predicts gene function and provides a global view of embryonic patterning., Mech Dev 1998                                                              
Most Recent Morpholinos Do Not Elicit an Innate Immune Response during Early Xenopus Embryogenesis., Dev Cell 2019          
All View All Papers 6 paper(s) referencing morpholinos 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 23 terms 9 terms 8 terms
PANTHER crx
KEGG Pathways K09326 K09326 K18490
KOG [K] Homeobox transcription factor
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks crx
Antibodies Crx Ab1 Crx Ab1 Crx Ab1
Morpholinos crx MO1 crx MO1 crx MO1
ORFs crx.L ORF1 crx.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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