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Summary Expression Gene Literature (170) GO Terms (21) Nucleotides (198) Proteins (42) Interactants (1808) Wiki
Gene Symbol:

Gene Name:
notochord homeobox

Xnot , noto , Xnot-2 , Xnot2 , flh , floating head , Znot , not-a , not-b , not1 , Xnot1 ( Add synonyms , Nomenclature history )

Gene Function:
homeodomain transcription factor

Protein Function :
Transcriptional repressor. Plays a fundamental role in notochord formation, acting within the mesodermal region. Acts downstream of gsc and upstream of chrd and foxa4-A/pintallavis.

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External Links:
Xenbase Gene ID XB-GENE-478518 XB-GENE-6252631 XB-GENE-865187
Gene Symbol not not.L not.S
Chromosome Chr1 chr1L chr1S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100038059
mRNA RefSeq RefSeq RefSeq
Protein RefSeq RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine not not.L not.S
Phenotype X. tropicalis X. laevis.L X. laevis.S
Smith Morpholino Screen tgas141c24      
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
Protein Atlas
ZFIN, AGR noto ZFIN Ensembl
fruit fly
FLYBASE not Ensembl
First The evolution of vertebrate gastrulation., Dev Suppl 1992  
Most Recent Tissue segregation in the early vertebrate embryo., Semin Cell Dev Biol 2020  
All View All Papers 40 paper(s) referencing morpholinos 3 paper(s) referencing OMIMs 7 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 17 terms 7 terms 7 terms
KEGG Pathways
KOG [K] Transcription factor EMX1 and related HOX domain proteins
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks not
ORFs not.L ORF1 not.S ORF1
Clones EXRC Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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