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Summary Expression Gene Literature (891) GO Terms (27) Nucleotides (253) Proteins (46) Interactants (2532) Wiki
XB-GENEPAGE-478788
Gene Symbol:
tbxt

Gene Name:
T-box transcription factor T

Synonyms:
Xbra , X-bra , bra , Xbrachyury , brachyury , ntl , t-a , t-b , t ( Add synonyms , Nomenclature history )

Gene Function:
nuclear transcription factor

Protein Function :
Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Causes dorsal mesodermal differentiation of animal cap ectoderm when co-expressed with wnt8 and ...[+]



Interactants:
Loading ...

Diseases: 


OMIM:
NEURAL TUBE DEFECTS, SUSCEPTIBILITY TO; NTD [+]

External Links:
GEO Series :
GSE48663.
1/6
 
Xenbase Gene ID XB-GENE-478789 XB-GENE-6255736 XB-GENE-865212
Gene Symbol tbxt tbxt.L tbxt.S
Chromosome Chr05 chr5L chr5S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 493501
432248
399275
mRNA RefSeq RefSeq RefSeq
Protein RefSeq RefSeq RefSeq Swiss-Prot
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine tbxt tbxt.L tbxt.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen tgas116l23      
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards TBXT OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR T MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Tbxt Ensembl
zebrafish
ZFIN, AGR tbxtb tbxta ZFIN Ensembl
chicken
GEISHA TBXT Ensembl
fruit fly
FLYBASE t Ensembl
worm
Publications
First Identification of regulatory sequences in the prelude sequences of an H2A histone gene by the study of specific deletion mutants in vivo., Proc Natl Acad Sci U S A 1980  
Most Recent Brachyury in the gastrula of basal vertebrates., Mech Dev 2020  
All View All Papers 207 paper(s) referencing morpholinos 12 paper(s) referencing OMIMs 19 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 23 terms 4 terms 10 terms
PANTHER tbxt
KEGG Pathways K12190 [+] K10172 K10172
KOG [K] TBX2 and related T-box transcription factors
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks tbxt
Mutants Xtr.tbxtemJcsm , Xtr.tbxt,tbxt.2emJcsm
Antibodies T Ab1 , T Ab2 T Ab1 , T Ab2 T Ab1 , T Ab2
Morpholinos tbxt MO1 , tbxt MO2 , tbxt MO3 , tbxt MO4 tbxt MO1 , tbxt MO2 , tbxt MO3 , tbxt MO4 tbxt MO1 , tbxt MO2 , tbxt MO3 , tbxt MO4
ORFs tbxt ORF1 tbxt.L ORF1 tbxt.S ORF1
Clones EXRC Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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