t Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (480)

Nucleotides (229)

Interactants (931)

XB-GENEPAGE-478788

Gene Symbol: t Gene Name: T, brachyury homolog Synonyms: Xbra, X-bra, bra, Xbrachyury, brachyury, ntl, bu Add Xenopus synonyms Gene Function: T-box transcription factor Interactants: gsc(158) , chrd(121) , myod1(78) , wnt8a(76) , nodal(68) , odc1(58) , otx2(58) View All	1/4

XB-GENE-478789

XB-GENE-865212

XB-GENE-6255736

Molecules		tropicalis	laevis a		laevis b
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene		Entrez Gene
mRNA		Refseq >NM_001008138\|Xenopus (Silurana) tropicalis T, brachyury homolog (t), mRNA ATTTACTACCTGCCGATCATTCACACCTTGGGTTTTGTTCCGATTACAATAAGAGAAATCAGAGGAAGAGCTGCTGTTAGTTTCCCCCCAGTGTGTGCGCTTGGAAGCCCCTCTCTTGAGGAATGAGTGTAAGTGCCACCGAGAGCTGCGCAAAGAATGTGCAGTACCGGGTCGATCACCTTCTCAGCGCTGTGGAGAATGAGCTCCAGGCTGGCAGCGAGAAGGGGGACCCCACCGAGAAGGAGCTGAAGGTGAGCCTGGAGGAGCGGGACCTGTGGATGAGGTTCAAGGAGCTCACCAATGAGATGATCGTCACCAAGAATGGAAGGCGAATGTTTCCAGTTCTAAAGGTGAGCGTGTCGGGCCTGGATCCCAATGCCATGTACACATTTCTGCTGGATTTTGTGGCAGCTGACAACCACCGCTGGAAGTACGTGAATGGAGAATGGGTTCCAGGTGGCAAACCTGAGCCCCAGGCCCCCAGTTGTGTTTACATTCACCCAGACTCCCCCAACTTTGGAGCCCACTGGATGAAAGATCCTGTTTCTTTCAGCAAAGTCAAACTTACAAACAAAATGAATGGTGGAGGCCAGATTATGCTAAACTCGTTGCACAAATATGAACCTCGAATCCACATAGTGAGAGTTGGAGGCACCCAGAGAATGATCACCAGTCACTCATTTCCTGAGACACAGTTCATAGCAGTGACAGCATACCAGAATGAAGAGATTACAGCACTTAAAATCAAACACAACCCCTTTGCCAAAGCATTTCTGGATGCAAAAGAAAGAAATGATTATAAAGACATCTTGGATGAGGGTATTGATAGTCAACACTCAAATTTCTCTCAGCTAGGTACTTGGCTGATTCCCAACGGTGGATCTTTATGTTCGCCCAATCCACACACACAGTTCGGGGCGCCGATTTCTCTATCGTCTCCTCATGGCTGCGAGCGATACTCATCTCTAAGAAACCACCGCTCGGCTCCCTACCCAAGTCCATATGTTCACAGAAACAATTCCCCAAACAATTTAGCAGATAATTCTTCAGCCTGTCTTTCAATGCTCCAGTCCCATGATAACTGGTCCACACTTCAAATGCCGGCACACACTGGGATGTTGCCAATGAGTCACAGCGCGGGAACACCTCCTACCTCAAGTCAGTACCCTTCCTTGTGGTCTGTGAGTAACAGCACCCTCACACCAGTGTCTCAGTCTGGAGGAATAACTAATGGAATAAGCTCCCAGTACTTACGCGGCTCTACGCCTCATTACTCATCTCTTTCACATGCTGTTCCCTCACCAGCCACAGGATCTCCATTGTATGAACATGGATCACAAACAGAAATAGCAGAAAACCAGTATGACGTCACAGCACATTCCAGGCTTTCATCAACATGGACAACAGTTGCACCGCCGTCAATCTAAAGCAAAGACTTTAAGGACTTAATATAAAAATCAGTGTTTCCTGGGCTTGAGCTGCTGGGGGTCCCTGGCCCATAAAAGCAAATTACCAAAACAACTTGAAGATGTTCTTGCAATAATTAAGTTGGCTTTTACCTGTTTCAAAAGGCTTCACTGGTCCAACCAGGTGTGAGTGGTCTGCACTGCAGCTCACTATCTTGAGAAGCAAAGCACAAACAAAAGTAGGATTCACTTAGGTGATAAAACCAACAATCGTTATTACCTTAGAATATGTTATGTTGCCTATGTATGTTCTACATCAGTTTTCTGAATGTGCTGGCAAAGGGTAATTTACCCAGGAGGCTCTTTTGAAGGGAATTTAAAGATGCAGGAAAACGGAAACTGTATTAATAAGAGAATCCATTCTGCTTATTTCTTTTACAATCCCTATTTACTTCTATCTGGGACTGCTGCTACAGGCTACATGGTTTTTTATTATAGACATATTTTTAATATGCCTTATTAAGTGAAAATAATTTAAAATGCTTAAATAATTTAAAATGTGGTACTGTCTAGAGTCTAGAGACTCTAGACTATGAAAAAATATTTGCAGCAGAATTTGTTTGCATCTACTGTGTCAGACAAGTTATTATCTGCTGCCTAAATAACTGCAAACTGCACCCAGCTAAATTGATTTTAAATATTGTTTCTAAAACACAAAGAGAAAGTATCCTAATTCATTGTGTAACTGGTATTGCTGTATTTATTTTTTCCATGTGACTTCCATGTGATGTTTTTGTGGTAAATGTATATGTGCTGTAAATATGTTATTGTATGCTGTAAGACAATCAGATAAAAAAATACTGTGGAACAGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001090578\|Xenopus laevis T, brachyury homolog (t-a), mRNA CTTTAATGTCAATTGGATTTACTACCTGCCGATCACTCGCACCTTGGGTTTTGTTCCGATTACAATAAAACAAATCAGTGGAAAAGCTGCTGTAAGTTTTTTTTGCCCCTGTTTGTGTGTTTGGACCCCCCTCTCTGGAGTAATGAGTGCGACCGAGAGCTGCGCCAAGAACGTACAGTACCGGGTGGATCATCTTCTCAGCGCTGTGGAGAATGAGCTCCAGGCTGGCAGCGAGAAGGGGGACCCCACCGAGAAGGAGCTGAAGGTTAGCCTGGAGGAGCGGGACCTGTGGACGAGGTTCAAGGAGCTCACCAACGAGATGATCGTCACCAAGAATGGAAGACGAATGTTTCCAGTTCTGAAGGTGAGCATGTCGGGCCTGGATCCCAATGCAATGTATACGGTTCTGCTGGACTTTGTGGCAGCCGACAACCACCGCTGGAAGTATGTGAATGGAGAATGGGTTCCAGGTGGCAAACCCGAGCCCCAGGCCCCCAGTTGTGTTTATATCCACCCAGACTCACCCAACTTTGGAGCCCACTGGATGAAAGATCCTGTCTCTTTTAGCAAAGTCAAACTTACAAACAAAATGAATGGTGGAGGCCAGATTATGTTAAACTCTTTGCACAAGTATGAACCTCGAATCCACATAGTGAGAGTTGGTGGCACCCAGAGAATGATCACTAGCCATTCATTCCCTGAGACACAGTTCATAGCAGTGACCGCATACCAGAATGAAGAGATTACAGCACTTAAAATCAAACACAATCCATTTGCCAAAGCATTTCTTGATGCAAAAGAAAGAAATGATTATAAAGACATCTTGGATGAGGGAATCGATAGTCAGCATTCTAATTTCTCTCAATTAGGTACTTGGCTTATTCCTAATGGTGGGTCATTATGTTCGCCCAATCCACACACTCAGTTCGGGGCACCTCTCTCTCTATCGTCACCTCATGGCTGTGAGCGATACTCATCTCTAAGGAACCACCGCTCAGCTCCTTACCCCAGTCCGTACACTCACAGAAACAATTCTCCAAACAATTTAGCAGATAATTCTTCAGCCTGTCTGTCAATGCTCCAGTCCCATGATAACTGGTCTACCCTTCAAATGCCAGCACACACTGGGATGTTGCCAATGAGTCACAGCACGGGAACACCACCTCCCTCAAGTCAGTACCCTTCTTTATGGTCTGTGAGTAACAGTGCCATCACACCAGTGTCTCAGTCTGGAGGAATAACTAATGGAATAAGCTCCCAGTACTTACTTGGCTCTACACCTCACTACTCGTCTCTTTCACATGCTGTGCCCTCACCATCCACAGGATCTCCATTGTATGAGCATGGAGCACAAACAGAAATAGCAGAAAACCAGTATGATGTCACGGCACATTCCAGGCTTTCATCAACATGGACACCCGTTGCGCCACCATCAGTCTAAAGTAAAGACCTTGAGGACTCAGTATAAAAATCAGTATTTCCTGGGCCTGAATTGCTGGGGGTCCCTGGTACATAAAGCAAATGATTGCTGTAGGCCTCCAAAACAACTTAAAGATGTGCTTAGGCAAGTTATATCAGTGTTTACCTGCTTCTAAAGACTTCATGGGCCCAACCAGGTGTGGGTGGTCTGCTCAGCGGGCCACCATATGGATATAGATGCTTAGCACAAAGTGGGGTTAACTTACACATATTAAGTGATTACACCAAGGATCGTTATCACCTCTGTATATTCTACATCATTTTTCTGAATGTACTGGCAAGGGGTGATTTACCCAGGAGTCTCTTTTAAAGGGAATGTAAAAATACAGTATTAATAAGAAGGTCTGCTTCTTTTTTACACTGCCTTTATATTGCTATAAATTACTTTTATTTGGGACTGCTGCTACAGACTACACATTTTTATTATAGACATATTTTTTTTAATATGCCTTATTAAGTAAAAAATAATTTAAAATGTTTAAATAATTTAAAATGTGGTACTGTCTAGATTATGGAAAAATATTGGAAGCAGCTTTTGTCTGAATCTGCTACTTGCTGCCTAAATAACCACAAACTTCTCCCAGCTAAACTGATTTGAAATATGGTTTCTAAAAAAATAACGGGGAGAGAAAGTATGTTATATCATTGTGTAACTGGTATTGCTGTATTTATTTTATCTTCATGTTTTTGTGGTAAATGTATATGTGCTGTAAATATGTTATTGTATGCTGTAAGACAATCCGATAAAAGAAATATTGTGGAACAGAAAAAAAAAAAAAAAAAAAA		Refseq >NM_001091696\|Xenopus laevis T, brachyury homolog (t-b), mRNA CCCTAATGTCAATTGGATTTACTACCTGCTGATCAATCGCACCTTGGGTTTTGTTCCGATTAGTGGAAAAGCTGCTAAAATTTTTCCCCCAGTCTGTGTGTTACGAAGCCTCCCTTTCTGGAGGAATGAGTGCGACCGAGAGCTGCGCCAAGAACGTGCAGTACCGGGTAGATCATCTGCTGAGCGCTGTGGAGAATGAGCTCCAGGCTGGCAGCGAAAAGGGGGACCCCACCGAGAAGGAGCTGAAGGTGAGTCTGCAGGAGCGGGACCTGTGGACGAGGTTTAAGGAGCTCACCAATGAGATGATCGTCACTAAGAATGGAAGGAGAATGTTTCCAGTTCTGAAGGTGAGCGTGTCGGGCCTGGATCCCAATGCCATGTACACGGTTCTTCTGGACTTTGTGGCAGCTGACAACCTCCGCTGGAAGTATGTGAATGGAGAATGGGTTCCAGGTGGCAAACCTGAGCCCCAGGCCCCTAGTTGTGTTTACATCCACCCAGATTCCCCCAATTTTGGAGCCCACTGGATGAAAGATCCTGTGTCTTTTAGCAAAGTCAAACTTACAAACAAAATGAATGGTGGAGGCCAGATTATGTTAAACTCTTTGCACAAGTATGAACCTCGAATCCACATTGTGAGAGTTGGCGGCACCCAGAGAATGATCACCAGCCATTCATTCCCTGAGACACAGTTCATAGCAGTGACCGCATACCAGAATGAAGAGATTACAGCACTTAAAATCAAGCACAACCCATTTGCCAAAGCATTTCTTGATGCAAAAGAAAGAAATGATTATAAAGACATCTTGGATGAGGGAATTAATAGTCAGCACTCAAATTTCTCTCAGTTAGGTACTTGGCTCATTCCTAATGGTGGATCATTATGTACGCCCAATCCACACACTCAGTTCGGGGCACCTCTCTCTCTATCATCTCCTCATGGCTGTGAGCGATACTCATCTCTGAGGAACCACCGCTCCGCTCCTTACCCCAGTCCATACACTCACAGAAACAATTCTCCAAACAATTTAACAGATAATTCCTCAGCATGTCTTTCAATGCTCCAGTCCCATGGCAACTGGTCCACACTTCAAATGCCAGCACACACAGGGATGTTGCCAATGAGTCACAGCACAGGAACACCACCTACCTCAAGTCAGTACACTTCTTTGTGGTCTGTAAGTAACAGTACCATCACACCAGTGTCTCAGTCTGGAGGAATAAGTAATGGAACAAGTCCCCAGTACCTACGTGGCTCTACACCTCATTACTCATCTCTTTCACATGCTGTGCCCTCACCAACCACAGGATCCCCATTGTATGAACATGGAGCACAAACAGAAATAGCAGAAAACCAGTATGATGTCACTGCACATTCCAGGCTTTCATCAGCATGGACACCAGTTGCACCACCATCAATCTAAAGTAAAGACTATAAGGACTTAATACACAAATCAGTATTTCCTGGGCCAAGTAGCTGAGTGTCCATGGCCCATAAAGCAAATGATTGCTGCAGGCCTCCCAAATAACTTAAAGTTGTGCTTAGGCTAGTTATGTCAGCCTTTCCCTGCTTCTAAAGGCTTCATGGATCCAACCAGGCATGGGTGGTCTGCTCAGTGGGTCACCATCTTGAGATGCTTAACACAAAGTTGGTTTGACTTACATATAAGTGCAACATATAGGTTCTATTACCTGTATATTCTATGTCAGTTTTCTGAATGTACTGGCAAGGGGTGATTTATCCAGGAGGCTCTTCTAAAGGGAATGTAAAGATACAGTATTGCTTAATTACAGTATTAACTAAGATCCATTCTGCTTTTTTTAAAACATTCCCTCTATTGTTCTAAATTACTTTTATCTGAGACTGCTGCCTGCTGCTACAGAGTCAGACTACATGTTTTTTATTATAGACATATTTTAAATATGCCTTTTTAAGTAAACCTAATTTAATATGTTTAAATAATTTAAAATGTGGTACTGTCCAGATCATGGGAAAATATTTAGAGCAGTATTTGTCTGAATCTGCTGTGTCAGATTATCTGCTGCCTAAATACCCACAAACTGCACCAAGCTAGGTTAATTCTAAATAGTTTTTCCAAAAACTGAAGAGAACGTATGCTTTTCATTGTGTAACTGGTATTTCTGTATTTATTTTTTCCATGTGGCCATGTTTTTTGTGGTTAATGTATATGTACTGTAAACATGTTATTGTATGCTGAAAGACGATCTCTTTTGCCCCACTGAAGTGCAGTGTAAGGTATCTACCAATCTACACGTTGATGTGGGGGACCATGTGATGCTTCAATAAATACACTATTTTTTCAAAAAAAAAAAAAAA
Protein		Refseq >NP_001008139\|T, brachyury homolog [Xenopus (Silurana) tropicalis] MSVSATESCAKNVQYRVDHLLSAVENELQAGSEKGDPTEKELKVSLEERDLWMRFKELTNEMIVTKNGRRMFPVLKVSVSGLDPNAMYTFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKDPVSFSKVKLTNKMNGGGQIMLNSLHKYEPRIHIVRVGGTQRMITSHSFPETQFIAVTAYQNEEITALKIKHNPFAKAFLDAKERNDYKDILDEGIDSQHSNFSQLGTWLIPNGGSLCSPNPHTQFGAPISLSSPHGCERYSSLRNHRSAPYPSPYVHRNNSPNNLADNSSACLSMLQSHDNWSTLQMPAHTGMLPMSHSAGTPPTSSQYPSLWSVSNSTLTPVSQSGGITNGISSQYLRGSTPHYSSLSHAVPSPATGSPLYEHGSQTEIAENQYDVTAHSRLSSTWTTVAPPSI	Refseq >NP_001084047\|brachyury protein [Xenopus laevis] MSATESCAKNVQYRVDHLLSAVENELQAGSEKGDPTEKELKVSLEERDLWTRFKELTNEMIVTKNGRRMFPVLKVSMSGLDPNAMYTVLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKDPVSFSKVKLTNKMNGGGQIMLNSLHKYEPRIHIVRVGGTQRMITSHSFPETQFIAVTAYQNEEITALKIKHNPFAKAFLDAKERNDYKDILDEGIDSQHSNFSQLGTWLIPNGGSLCSPNPHTQFGAPLSLSSPHGCERYSSLRNHRSAPYPSPYTHRNNSPNNLADNSSACLSMLQSHDNWSTLQMPAHTGMLPMSHSTGTPPPSSQYPSLWSVSNSAITPVSQSGGITNGISSQYLLGSTPHYSSLSHAVPSPSTGSPLYEHGAQTEIAENQYDVTAHSRLSSTWTPVAPPSV UniProtKB		Refseq >NP_001085165\|T, brachyury homolog [Xenopus laevis] MSATESCAKNVQYRVDHLLSAVENELQAGSEKGDPTEKELKVSLQERDLWTRFKELTNEMIVTKNGRRMFPVLKVSVSGLDPNAMYTVLLDFVAADNLRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKDPVSFSKVKLTNKMNGGGQIMLNSLHKYEPRIHIVRVGGTQRMITSHSFPETQFIAVTAYQNEEITALKIKHNPFAKAFLDAKERNDYKDILDEGINSQHSNFSQLGTWLIPNGGSLCTPNPHTQFGAPLSLSSPHGCERYSSLRNHRSAPYPSPYTHRNNSPNNLTDNSSACLSMLQSHGNWSTLQMPAHTGMLPMSHSTGTPPTSSQYTSLWSVSNSTITPVSQSGGISNGTSPQYLRGSTPHYSSLSHAVPSPTTGSPLYEHGAQTEIAENQYDVTAHSRLSSAWTPVAPPSI

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis a		laevis b
UniGene		Str.55517 [+] Str.66116	Xl.514		Xl.7970
Unigene EST Profile		EST Profile	EST Profile		EST Profile
GEO data			GEO		GEO
Images		286 expression image(s) for tropicalis and laevis

Phenotype		tropicalis	laevis a		laevis b
Smith Morpholino Screen		tgas116l23

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	T	OMIM:182940
mouse		MGI	T	All(41) Radiation Induced(17) Chemically Induced(6) Spontaneous(15) Targeted, other(2)
zebrafish			LOC100004296

Publications
First:		The ionic basis of the resting potential and a slow depolarizing response in Rohon-Beard neurones of Xenopus tadpoles. [J Physiol 1976]
Most recent:		Lin28 proteins are required for germ layer specification in Xenopus. [Development 2013]
		View All Papers 132 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		transcription factor activity
Biological:		regulation of transcription, DNA-dependent
Cellular Component:		nucleus
EC:
KOG:		[K] TBX2 and related T-box transcription factors

Reagents		tropicalis	laevis a		laevis b
Clones		EXRC - 2 clone(s)	EXRC - 2 clone(s)
		open biosystems	open biosystems		open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes		geneservice/RZPD imagenes
Affymetrix 1.0		Str.10814.1.S1_a_at [+] Str.48350.1.A1_at	Xl.514.1.S1_at
Affymetrix 2.0			Xl2.514.1.S1_at		Xl2.7970.1.S1_at

Symbol legend[+]