Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (14) GO Terms (10) Nucleotides (93) Proteins (34) Interactants (214) Wiki
XB-GENEPAGE-478797
Gene Symbol:
polg

Gene Name:
polymerase (DNA) gamma, catalytic subunit

Synonyms:
DNA polymerase gamma ( Add synonyms , Nomenclature history )

Gene Function:
mitochondrial DNA polymerase gamma, catalytic subunit

Protein Function :
Involved in the replication of mitochondrial DNA.


InterPro :
DEAD/DEAH box helicase dom , P-loop NTPase , RNA helicase DEAD Q motif , Helicase C [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
mitochondrial DNA depletion syndrome 1 [+]

OMIM:
MITOCHONDRIAL DNA DEPLETION SYNDROME 4A (ALPERS TYPE); MTDPS4A [+]

External Links:
 
Xenbase Gene ID XB-GENE-478798 XB-GENE-865213 XB-GENE-17338988
Gene Symbol polg polg.L polg.S
Chromosome Chr3 chr3L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2
CDS Gene model Gene model
Entrez Gene 100488393
397851
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein TrEMBL NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine polg polg.L polg.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards POLG OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Polg MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Polg Ensembl
zebrafish
ZFIN, AGR polg ZFIN Ensembl
chicken
GEISHA POLG Ensembl
fruit fly
Publications
First A phylogenetic study on vertebrate mitochondrial DNA polymerase., Eur J Biochem 1979  
Most Recent High variability of expression profiles of homeologous genes for Wnt, Hh, Notch, and Hippo signaling pathways in Xenopus laevis., Dev Biol 2017                    
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 8 terms 6 terms 0 term
PANTHER polg
KEGG Pathways K02332
KOG [L] Mitochondrial DNA polymerase gamma, catalytic subunit
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks polg
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info