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XB-GENEPAGE-478821
Gene Symbol:
map2k1
Gene Name: mitogen-activated protein kinase kinase 1
Synonyms:
mek1
( Gene Function: serine/threonine kinase Protein Function
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Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to th...[+]
InterPro
![]() Interactants:
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Diseases: Disease Ontology:
cardiofaciocutaneous syndrome
OMIM:
NOONAN SYNDROME 1; NS1
External Links:
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Xenbase Gene ID
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XB-GENE-478822 | XB-GENE-865216 | XB-GENE-17341792 | |||||
Gene Symbol | map2k1 | map2k1.L | map2k1.S | Chromosome | Chr3 | chr3L | chr3S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.2
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Version 9.1
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CDS |
Gene model
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Gene model
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Gene model
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Entrez Gene |
493420
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379991
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108712802
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mRNA |
RefSeq
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NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Proteomics | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Embryonic Protein Expression | Stage profile:![]() |
Stage profile:![]() |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | map2k1 | map2k1.L | map2k1.S | |||||
Orthology ![]() |
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human |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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Publications | ||||||||
First |
Molecular cloning and sequencing of a carp cDNA encoding mitogen-activated protein kinase kinase., Biochim Biophys Acta 1994 |
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Most Recent |
Predation threats for a 24-h period activated the extension of axons in the brains of Xenopus tadpoles., Sci Rep 2020 ![]() |
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All | View All Papers 3 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 3 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 25 terms | 10 terms | 2 terms | |||||
PANTHER | map2k1 | |||||||
KEGG Pathways | K04368 | K04368 | K04368 | |||||
KOG |
[T] Mitogen-activated protein kinase kinase (MAP2K)
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | map2k1 | |||||||
Antibodies | map2k1 Ab1 | map2k1 Ab1 | map2k1 Ab1 | |||||
Morpholinos | map2k1 AGT MO1 | map2k1 AGT MO1 , map2k1 MO2 | map2k1 AGT MO1 | |||||
ORFs | map2k1 ORF1 | map2k1.L ORF1 | ||||||
Clones | Horizon Source BioScience | Horizon Source BioScience | Horizon | |||||
Plasmids | Addgene | Addgene |
Symbol legend:



