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Summary Expression Gene Literature (23) GO Terms (6) Nucleotides (26) Proteins (12) Interactants (167) Wiki
XB-GENEPAGE-478929
Gene Symbol:
tll2

Gene Name:
tolloid like 2

Synonyms:
xolloid , Xld ( Add synonyms , Nomenclature history )

Gene Function:
metalloprotease

Protein Function :
Protease which specifically processes prolysyl oxidase and maybe also chordin. Required for the embryonic development. Predominant protease, which in the development, influences dorsal-ventral patterni...[+]


InterPro :
MetalloPept cat dom sf , BMP 1/tolloid-like , EGF-type Asp/Asn hydroxyl site , CUB dom [+]

Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-22062583 XB-GENE-478934 XB-GENE-17336748
Gene Symbol tll2 tll2.L tll2.S
Chromosome Chr07 chr7L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.1
CDS Gene model Gene model
Entrez Gene 105947755
399469
mRNA NCBI Nucleotide
Protein RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine tll2 tll2.L tll2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards TLL2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Tll2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Tll2 Ensembl
zebrafish
chicken
GEISHA TLL2 Ensembl
fruit fly
Publications
First The astacin family of metalloendopeptidases., J Biol Chem 1991  
Most Recent Generation of animal form by the Chordin/Tolloid/BMP gradient: 100 years after D''Arcy Thompson., Dev Growth Differ 2017              
All View All Papers 3 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 0 term 6 terms 0 term
PANTHER tll2
KEGG Pathways K13047
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks tll2
Morpholinos tll2 MO1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info